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Up-regulation of proBDNF/p75(NTR) signaling in antibody-secreting cells drives systemic lupus erythematosus

Inappropriate expansion of antibody-secreting cells (ASCs) is typical of systemic lupus erythematosus (SLE), but the regulatory signaling of pathogenic ASCs is unclear. The present study shows that brain-derived neurotrophic factor precursor (proBDNF) and its high-affinity pan-75 neurotrophin recept...

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Detalles Bibliográficos
Autores principales:	Shen, Wei-Yun, Luo, Cong, Hurtado, Plinio Reinaldo, Liu, Xiao-Jing, Luo, Ru-Yi, Li, Hui, Hu, Zhao-Lan, Xu, Jun-Mei, Coulson, Elizabeth J., Zhao, Ming, Zhou, Xin-Fu, Dai, Ru-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769540/ https://www.ncbi.nlm.nih.gov/pubmed/35044824 http://dx.doi.org/10.1126/sciadv.abj2797

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