A comprehensive long-read isoform analysis platform and sequencing resource for breast cancer

Tumors display widespread transcriptome alterations, but the full repertoire of isoform-level alternative splicing in cancer is unknown. We developed a long-read (LR) RNA sequencing and analytical platform that identifies and annotates full-length isoforms and infers tumor-specific splicing events....

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Detalles Bibliográficos
Autores principales: Veiga, Diogo F. T., Nesta, Alex, Zhao, Yuqi, Mays, Anne Deslattes, Huynh, Richie, Rossi, Robert, Wu, Te-Chia, Palucka, Karolina, Anczukow, Olga, Beck, Christine R., Banchereau, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769553/
https://www.ncbi.nlm.nih.gov/pubmed/35044822
http://dx.doi.org/10.1126/sciadv.abg6711

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