Fine-tuning of β-catenin in mouse thymic epithelial cells is required for postnatal T-cell development

In the thymus, the thymic epithelium provides a microenvironment essential for the development of functionally competent and self-tolerant T cells. Previous findings showed that modulation of Wnt/β-catenin signaling in mouse thymic epithelial cells (TECs) disrupts embryonic thymus organogenesis. How...

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Detalles Bibliográficos
Autores principales: Fujimori, Sayumi, Ohigashi, Izumi, Abe, Hayato, Matsushita, Yosuke, Katagiri, Toyomasa, Taketo, Makoto M, Takahama, Yousuke, Takada, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769649/
https://www.ncbi.nlm.nih.gov/pubmed/35042581
http://dx.doi.org/10.7554/eLife.69088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769649/
https://www.ncbi.nlm.nih.gov/pubmed/35042581
http://dx.doi.org/10.7554/eLife.69088

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