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Engineering CAR T cells for enhanced efficacy and safety

Despite its success in treating hematologic malignancies, chimeric antigen receptor (CAR) T cell therapy faces two major challenges which hinder its broader applications: the limited effectiveness against solid tumors and the nonspecific toxicities. To address these concerns, researchers have used s...

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Detalles Bibliográficos
Autores principales: Wu, Yiqian, Huang, Ziliang, Harrison, Reed, Liu, Longwei, Zhu, Linshan, Situ, Yinglin, Wang, Yingxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769768/
https://www.ncbi.nlm.nih.gov/pubmed/35071966
http://dx.doi.org/10.1063/5.0073746