Cargando…
Robust genome editing in adult vascular endothelium by nanoparticle delivery of CRISPR-Cas9 plasmid DNA
Vascular endothelium plays a crucial role in vascular homeostasis and tissue fluid balance. To target endothelium for robust genome editing, we developed poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide) (PEG-b-PLGA) copolymer-based nanoparticle formulated with polyethyleneimine. A...
Autores principales: | Zhang, Xianming, Jin, Hua, Huang, Xiaojia, Chaurasiya, Birendra, Dong, Daoyin, Shanley, Thomas P., Zhao, You-Yang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769807/ https://www.ncbi.nlm.nih.gov/pubmed/34986352 http://dx.doi.org/10.1016/j.celrep.2021.110196 |
Ejemplares similares
-
Delivery of CRISPR/Cas9 Plasmid DNA by Hyperbranched Polymeric Nanoparticles Enables Efficient Gene Editing
por: Xiu, Kemao, et al.
Publicado: (2022) -
Strategies in the delivery of Cas9 ribonucleoprotein for CRISPR/Cas9 genome editing
por: Zhang, Song, et al.
Publicado: (2021) -
Efficient CRISPR/Cas9 Plasmids for Rapid and Versatile Genome Editing in Drosophila
por: Gokcezade, Joseph, et al.
Publicado: (2014) -
Plasmid-Based CRISPR-Cas9 Gene Editing in Multiple Candida Species
por: Lombardi, Lisa, et al.
Publicado: (2019) -
Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing
por: Duan, Li, et al.
Publicado: (2021)