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Deep Learning Model for the Automatic Classification of White Blood Cells

Blood cell count is highly useful in identifying the occurrence of a particular disease or ailment. To successfully measure the blood cell count, sophisticated equipment that makes use of invasive methods to acquire the blood cell slides or images is utilized. These blood cell images are subjected t...

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Autores principales: Sharma, Sarang, Gupta, Sheifali, Gupta, Deepali, Juneja, Sapna, Gupta, Punit, Dhiman, Gaurav, Kautish, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769872/
https://www.ncbi.nlm.nih.gov/pubmed/35069725
http://dx.doi.org/10.1155/2022/7384131
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author Sharma, Sarang
Gupta, Sheifali
Gupta, Deepali
Juneja, Sapna
Gupta, Punit
Dhiman, Gaurav
Kautish, Sandeep
author_facet Sharma, Sarang
Gupta, Sheifali
Gupta, Deepali
Juneja, Sapna
Gupta, Punit
Dhiman, Gaurav
Kautish, Sandeep
author_sort Sharma, Sarang
collection PubMed
description Blood cell count is highly useful in identifying the occurrence of a particular disease or ailment. To successfully measure the blood cell count, sophisticated equipment that makes use of invasive methods to acquire the blood cell slides or images is utilized. These blood cell images are subjected to various data analyzing techniques that count and classify the different types of blood cells. Nowadays, deep learning-based methods are in practice to analyze the data. These methods are less time-consuming and require less sophisticated equipment. This paper implements a deep learning (D.L) model that uses the DenseNet121 model to classify the different types of white blood cells (WBC). The DenseNet121 model is optimized with the preprocessing techniques of normalization and data augmentation. This model yielded an accuracy of 98.84%, a precision of 99.33%, a sensitivity of 98.85%, and a specificity of 99.61%. The proposed model is simulated with four batch sizes (BS) along with the Adam optimizer and 10 epochs. It is concluded from the results that the DenseNet121 model has outperformed with batch size 8 as compared to other batch sizes. The dataset has been taken from the Kaggle having 12,444 images with the images of 3120 eosinophils, 3103 lymphocytes, 3098 monocytes, and 3123 neutrophils. With such results, these models could be utilized for developing clinically useful solutions that are able to detect WBC in blood cell images.
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spelling pubmed-87698722022-01-20 Deep Learning Model for the Automatic Classification of White Blood Cells Sharma, Sarang Gupta, Sheifali Gupta, Deepali Juneja, Sapna Gupta, Punit Dhiman, Gaurav Kautish, Sandeep Comput Intell Neurosci Research Article Blood cell count is highly useful in identifying the occurrence of a particular disease or ailment. To successfully measure the blood cell count, sophisticated equipment that makes use of invasive methods to acquire the blood cell slides or images is utilized. These blood cell images are subjected to various data analyzing techniques that count and classify the different types of blood cells. Nowadays, deep learning-based methods are in practice to analyze the data. These methods are less time-consuming and require less sophisticated equipment. This paper implements a deep learning (D.L) model that uses the DenseNet121 model to classify the different types of white blood cells (WBC). The DenseNet121 model is optimized with the preprocessing techniques of normalization and data augmentation. This model yielded an accuracy of 98.84%, a precision of 99.33%, a sensitivity of 98.85%, and a specificity of 99.61%. The proposed model is simulated with four batch sizes (BS) along with the Adam optimizer and 10 epochs. It is concluded from the results that the DenseNet121 model has outperformed with batch size 8 as compared to other batch sizes. The dataset has been taken from the Kaggle having 12,444 images with the images of 3120 eosinophils, 3103 lymphocytes, 3098 monocytes, and 3123 neutrophils. With such results, these models could be utilized for developing clinically useful solutions that are able to detect WBC in blood cell images. Hindawi 2022-01-12 /pmc/articles/PMC8769872/ /pubmed/35069725 http://dx.doi.org/10.1155/2022/7384131 Text en Copyright © 2022 Sarang Sharma et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sharma, Sarang
Gupta, Sheifali
Gupta, Deepali
Juneja, Sapna
Gupta, Punit
Dhiman, Gaurav
Kautish, Sandeep
Deep Learning Model for the Automatic Classification of White Blood Cells
title Deep Learning Model for the Automatic Classification of White Blood Cells
title_full Deep Learning Model for the Automatic Classification of White Blood Cells
title_fullStr Deep Learning Model for the Automatic Classification of White Blood Cells
title_full_unstemmed Deep Learning Model for the Automatic Classification of White Blood Cells
title_short Deep Learning Model for the Automatic Classification of White Blood Cells
title_sort deep learning model for the automatic classification of white blood cells
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769872/
https://www.ncbi.nlm.nih.gov/pubmed/35069725
http://dx.doi.org/10.1155/2022/7384131
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