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Detection of minor variants in Mycobacterium tuberculosis whole genome sequencing data

The study of genetic minority variants is fundamental to the understanding of complex processes such as evolution, fitness, transmission, virulence, heteroresistance and drug tolerance in Mycobacterium tuberculosis (Mtb). We evaluated the performance of the variant calling tool LoFreq to detect de n...

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Detalles Bibliográficos
Autores principales:	Goossens, Sander N, Heupink, Tim H, De Vos, Elise, Dippenaar, Anzaan, De Vos, Margaretha, Warren, Rob, Van Rie, Annelies
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Case Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769888/ https://www.ncbi.nlm.nih.gov/pubmed/34962257 http://dx.doi.org/10.1093/bib/bbab541

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