Caracterización y factores pronóstico de mortalidad en pacientes ingresados en UCI por COVID-19 en un hospital público de referencia en Bogotá, Colombia

INTRODUCTION: Millions of deaths have been reported in the world due to COVID-19 infection, most described in patients admitted to intensive care units (ICU). The prognosis of the patient depends on the history and laboratory tests; for this reason, it is important to evaluate the characteristics of this population and determine risk factors for mortality at the local level. OBJECTIVE: To characterize and identify the prognostic factors associated with mortality in patients admitted to ICU with a diagnosis of COVID-19 infection in a public referral hospital in Bogotá, Colombia. MATERIALS AND METHODS: Retrospective, analytical, observational study in adults hospitalized in ICUs between March and August 2020. RESULTS: Sixty-eight patients were analysed, median age was 59 (IQR 19.0) years; 55.9% male. A percentage of 97.1 required mechanical ventilation, with a median PaO(2)/FiO(2) on admission of 91.5. A percentage of 82.4 presented shock requiring vasopressor; 33% of the patients received dialysis support, being greater in the group that died (53.8 vs. 19.0%, P = .004). Mortality was 38.2% and in the multivariate analysis it was associated with the serum lactate level at admission measured in arterial gases, greater than 2 mmol/L (OR = 4.19; 95% CI 1.13-15.55), admission ferritin greater than 1500 μg/L (OR = 4.18; 95% CI 1.20-14.58) and the requirement for dialysis support during the ICU stay (OR = 7.64; 95% CI 2.00-29.14). CONCLUSION: The prognostic factors associated with mortality were elevated lactate, elevated ferritin, and requirement for dialysis support.