Toll-like receptor 4-mediated necroptosis in the development of necrotizing enterocolitis

BACKGROUND: Dramatic intestinal epithelial cell death leading to barrier dysfunction is one of the mechanism of neonatal necrotizing enterocolitis (NEC), in which Toll-like receptor 4 (TLR4) plays a pivotal role. This study explored the role of necroptosis, a drastic way of cell death in NEC. METHOD...

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Detalles Bibliográficos
Autores principales: Liu, Tianjing, Zong, Haifeng, Chen, Xiaoyu, Li, Sihang, Liu, Ziyun, Cui, Xuewei, Jia, Guoqiang, Shi, Yongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Basic Science Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770135/
https://www.ncbi.nlm.nih.gov/pubmed/33731807
http://dx.doi.org/10.1038/s41390-021-01457-y

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