A review of required monitoring and management of physical health parameters in patients being treated with clozapine

AIMS: To review available standards for physical health monitoring in people taking clozapine To audit current practice against standards To identify changes in practice and facilitate a re-audit to assess impact of any changes METHOD: Standard: CG178 Psychosis and Schizophrenia in Adults: Prevention and Management – NICE, February 2014 Target:100% Exceptions: None Sample: The original audit included all 58 patients from the Worcester clozapine clinic, as per October 2018. The re-audit reviewed a random sample of all patients attending the clozapine clinics in Worcester, Kidderminster and Redditch, as part of Worcestershire Health and Care NHS Trust, as per October 2019. A total of 66 patients were selected. Data Source: Carenotes and ICE RESULT: Areas of good practice: Monitoring of HbA1c and FBC remains good There has been an improvement in monitoring alcohol use, substance misuse and side effects Areas requiring improvement: There continues to be limited recording of respiratory rate There has been a decline in recording temperature, BMI and concomitant therapies Potential reasoning for missing data includes: Staff not knowing the monitoring requirements, which is more likely to be an issue when staff members running the clinics change frequently Monitoring being completed but not documented Patients’ refusal of monitoring Data being recorded in alternative locations including general practice, without communication between services Patients moving between teams or having inpatient stays may disrupt monitoring regime CONCLUSION: LIMITATIONS This audit assumes all patients involved to be on a stable dose of clozapine with routine monitoring Some patients may have been transferred between teams or inpatients during the period of data collection There is no scope to record when patients refuse monitoring We may not have access to all notes such as those from general practice for data collection RECOMMENDATIONS Induction programme for junior doctors to include education on clozapine monitoring Training for staff involved in clozapine clinics to ensure better understanding of monitoring requirements Procurement of ECG machines for each site and relevant training for nursing and medical staff Collaboration with GPs for shared data Re-audit in 1 year