WNT/beta-catenin signalling interrupts a senescence-induction cascade in human mesenchymal stem cells that restricts their expansion

Senescence, the irreversible cell cycle arrest of damaged cells, is accompanied by a deleterious pro-inflammatory senescence-associated secretory phenotype (SASP). Senescence and the SASP are major factors in aging, cancer, and degenerative diseases, and interfere with the expansion of adult cells i...

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Detalles Bibliográficos
Autores principales: Lehmann, Johannes, Narcisi, Roberto, Franceschini, Natasja, Chatzivasileiou, Danai, Boer, Cindy G., Koevoet, Wendy J. L. M., Putavet, Diana, Drabek, Dubravka, van Haperen, Rien, de Keizer, Peter L. J., van Osch, Gerjo J. V. M., ten Berge, Derk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770385/
https://www.ncbi.nlm.nih.gov/pubmed/35048158
http://dx.doi.org/10.1007/s00018-021-04035-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770385/
https://www.ncbi.nlm.nih.gov/pubmed/35048158
http://dx.doi.org/10.1007/s00018-021-04035-x

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