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Turning Platelets Off and On: Role of RhoGAPs and RhoGEFs in Platelet Activity
Platelet cytoskeletal reorganisation is a critical component of platelet activation and thrombus formation in haemostasis. The Rho GTPases RhoA, Rac1 and Cdc42 are the primary drivers in the dynamic reorganisation process, leading to the development of filopodia and lamellipodia which dramatically i...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770426/ https://www.ncbi.nlm.nih.gov/pubmed/35071371 http://dx.doi.org/10.3389/fcvm.2021.820945 |