The mitochondrial β-oxidation enzyme HADHA restrains hepatic glucagon response by promoting β-hydroxybutyrate production

Disordered hepatic glucagon response contributes to hyperglycemia in diabetes. The regulators involved in glucagon response are less understood. This work aims to investigate the roles of mitochondrial β-oxidation enzyme HADHA and its downstream ketone bodies in hepatic glucagon response. Here we sh...

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Detalles Bibliográficos
Autores principales: Pan, An, Sun, Xiao-Meng, Huang, Feng-Qing, Liu, Jin-Feng, Cai, Yuan-Yuan, Wu, Xin, Alolga, Raphael N., Li, Ping, Liu, Bao-Lin, Liu, Qun, Qi, Lian-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770464/
https://www.ncbi.nlm.nih.gov/pubmed/35046401
http://dx.doi.org/10.1038/s41467-022-28044-x

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