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Abnormal whole-body energy metabolism in iron-deficient humans despite preserved skeletal muscle oxidative phosphorylation

Iron deficiency impairs skeletal muscle metabolism. The underlying mechanisms are incompletely characterised, but animal and human experiments suggest the involvement of signalling pathways co-dependent upon oxygen and iron availability, including the pathway associated with hypoxia-inducible factor...

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Detalles Bibliográficos
Autores principales: Frise, Matthew C., Holdsworth, David A., Johnson, Andrew W., Chung, Yu Jin, Curtis, M. Kate, Cox, Pete J., Clarke, Kieran, Tyler, Damian J., Roberts, David J., Ratcliffe, Peter J., Dorrington, Keith L., Robbins, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770476/
https://www.ncbi.nlm.nih.gov/pubmed/35046429
http://dx.doi.org/10.1038/s41598-021-03968-4