Cargando…

Overexpression of the SARS-CoV-2 receptor angiotensin converting enzyme 2 in cardiomyocytes of failing hearts

Hospitalized patients who die from Covid-19 often have pre-existing heart disease. The SARS-CoV-2 virus is dependent on the ACE2 receptor to be able to infect cells. It is possible that the strong link between cardiovascular comorbidities and a poor outcome following a SARS-CoV-2 infection is someti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vukusic, Kristina, Thorsell, Annika, Muslimovic, Aida, Jonsson, Marianne, Dellgren, Göran, Lindahl, Anders, Sandstedt, Joakim, Hammarsten, Ola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770525/ https://www.ncbi.nlm.nih.gov/pubmed/35046458 http://dx.doi.org/10.1038/s41598-022-04956-y

Ejemplares similares

Hypoxic cardiac fibroblasts from failing human hearts decrease cardiomyocyte beating frequency in an ALOX15 dependent manner
por: Sandstedt, Mikael, et al.
Publicado: (2018)

The Atrioventricular Junction: A Potential Niche Region for Progenitor Cells in the Adult Human Heart
por: Vukusic, Kristina, et al.
Publicado: (2019)

Human intracardiac SSEA4+CD34 cells show features of cycling, immature cardiomyocytes and are distinct from Side Population and C-kit+CD45- cells
por: Sandstedt, Mikael, et al.
Publicado: (2022)

Metagenomic sequencing of human cardiac tissue reveals Microbial RNA which correlates with Toll-like receptor-associated inflammation in patients with heart disease
por: Sandstedt, Joakim, et al.
Publicado: (2023)

High Density Sphere Culture of Adult Cardiac Cells Increases the Levels of Cardiac and Progenitor Markers and Shows Signs of Vasculogenesis
por: Vukusic, Kristina, et al.
Publicado: (2013)

Correction: Numerical Analysis of Etoposide Induced DNA Breaks
por: Muslimović, Aida, et al.
Publicado: (2009)

Numerical Analysis of Etoposide Induced DNA Breaks
por: Muslimović, Aida, et al.
Publicado: (2009)

Use of the cell division assay to diagnose Fanconi anemia patients' hypersensitivity to mitomycin C
por: Hammarsten, Ola, et al.
Publicado: (2020)

The Liver and Kidneys mediate clearance of cardiac troponin in the rat
por: Muslimovic, Aida, et al.
Publicado: (2020)

Angiotensin-Converting Enzyme-2
por: Clarke, Nicola E., et al.
Publicado: (2013)

How is cardiac troponin released from cardiomyocytes?( )
por: Hammarsten, Ola, et al.
Publicado: (2022)

Aliskiren in Patients Failing to Achieve Blood Pressure Targets With Angiotensin Converting Enzyme Inhibitors or Angiotensin Receptor Blockers
por: Hawkins, Elizabeth B., et al.
Publicado: (2012)

Dietary Potassium Downregulates Angiotensin-I Converting Enzyme, Renin, and Angiotensin Converting Enzyme 2
por: Vio, Carlos P., et al.
Publicado: (2020)

Angiotensin-Converting Enzyme 2 and Antihypertensives (Angiotensin Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors) in Coronavirus Disease 2019
por: Sanchis-Gomar, Fabian, et al.
Publicado: (2020)

Angiotensin converting enzyme and sodium glucose cotransporter inhibitors alleviate inflammatory effects of SARS-CoV-2 in cardiomyocytes
por: Wong, Chun-Ka, et al.
Publicado: (2022)

Angiotensin-Converting Enzyme 2 and the Resolution of Inflammation: In Support of Continuation of Prescribed Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers
por: Gersh, Felice L.
Publicado: (2020)

Angiotensin-converting enzyme 2 and new insights into the renin–angiotensin system
por: Lambert, Daniel W., et al.
Publicado: (2008)

Angiotensin-Converting Enzyme 2: The First Decade
por: Clarke, Nicola E., et al.
Publicado: (2012)

Angiotensin-converting enzyme 2 in lung diseases
por: Kuba, Keiji, et al.
Publicado: (2006)

In reply—Angiotensin-Converting Enzyme 2 and the Resolution of Inflammation: In Support of Continuation of Prescribed Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers
por: Sanchis-Gomar, Fabian, et al.
Publicado: (2020)

The Impact of Angiotensin-Converting Enzyme-2/Angiotensin 1-7 Axis in Establishing Severe COVID-19 Consequences
por: Maranduca, Minela Aida, et al.
Publicado: (2022)

Manipulating angiotensin metabolism with angiotensin converting enzyme 2 (ACE2) in heart failure
por: Patel, Vaibhav B., et al.
Publicado: (2012)

The Arachidonate 15-Lipoxygenase Enzyme Product 15-HETE Is Present in Heart Tissue from Patients with Ischemic Heart Disease and Enhances Clot Formation
por: Lundqvist, Annika, et al.
Publicado: (2016)

Angiotensin-(1-7), Angiotensin-Converting Enzyme 2, and New Components of the Renin Angiotensin System
por: Trask, Aaron J., et al.
Publicado: (2009)

Angiotensin Converting Enzymes
por: Wong, Marty K.S.
Publicado: (2016)

Angiotensin converting enzyme
por: Wong, Marty Kwok-Shing
Publicado: (2021)

Intrarenal Distributions and Changes of Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 in Feline and Canine Chronic Kidney Disease
por: MITANI, Sawane, et al.
Publicado: (2013)

Angiotensin-converting enzyme 2 expression is not induced by the renin–angiotensin system in the lung
por: Baba, Ryuta, et al.
Publicado: (2020)

Angiotensin-converting enzyme 2 and angiotensin 1–7: novel therapeutic targets
por: Jiang, Fan, et al.
Publicado: (2014)

Inhaled corticosteroids and angiotensin-converting enzyme-2 in COPD
por: Lipworth, Brian, et al.
Publicado: (2021)

Circulating angiotensin converting enzyme 2 and COVID-19
por: Leowattana, Wattana, et al.
Publicado: (2022)

Angiotensin-converting enzyme 2 in dogs with Dirofilaria immitis
por: Adin, Darcy B., et al.
Publicado: (2023)

Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2
por: Clayton, Daniel, et al.
Publicado: (2015)

Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Angiotensin-Converting Enzyme 2 Levels: A Comprehensive Analysis Based on Animal Studies
por: Kriszta, Gábor, et al.
Publicado: (2021)

Wide QRS‐T angles are associated with markers of increased inflammatory activity independently of hypertension and diabetes
por: Sandstedt, Mikael, et al.
Publicado: (2020)

Angiotensin Converting Enzyme 2, Angiotensin-(1-7), and Receptor Mas Axis in the Kidney
por: Pinheiro, Sergio Veloso Brant, et al.
Publicado: (2012)

Regulation of Cardiovascular Control Mechanisms by Angiotensin-(1–7) and Angiotensin-Converting Enzyme 2
por: Ferrario, Carlos M., et al.
Publicado: (2010)

Angiotensin-Converting-Enzyme 2 and Renin-Angiotensin System Inhibitors in COVID-19: An Update
por: Shukla, Ashwin Kumar, et al.
Publicado: (2021)

Effect of renin angiotensin blockers on angiotensin converting enzyme 2 level in cardiovascular patients
por: Farid fahmy, Sarah, et al.
Publicado: (2023)

Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19
por: Ni, Wentao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i0jqchhq4e8s7u6j58b3h73213