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Influenza Virus Down-Modulates G6PD Expression and Activity to Induce Oxidative Stress and Promote Its Replication

Influenza virus infection induces oxidative stress in host cells by decreasing the intracellular content of glutathione (GSH) and increasing reactive oxygen species (ROS) level. Glucose-6-phosphate dehydrogenase (G6PD) is responsible for the production of reducing equivalents of nicotinamide adenine...

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Detalles Bibliográficos
Autores principales: De Angelis, Marta, Amatore, Donatella, Checconi, Paola, Zevini, Alessandra, Fraternale, Alessandra, Magnani, Mauro, Hiscott, John, De Chiara, Giovanna, Palamara, Anna Teresa, Nencioni, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770543/
https://www.ncbi.nlm.nih.gov/pubmed/35071051
http://dx.doi.org/10.3389/fcimb.2021.804976