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Influenza Virus Down-Modulates G6PD Expression and Activity to Induce Oxidative Stress and Promote Its Replication
Influenza virus infection induces oxidative stress in host cells by decreasing the intracellular content of glutathione (GSH) and increasing reactive oxygen species (ROS) level. Glucose-6-phosphate dehydrogenase (G6PD) is responsible for the production of reducing equivalents of nicotinamide adenine...
Autores principales: | De Angelis, Marta, Amatore, Donatella, Checconi, Paola, Zevini, Alessandra, Fraternale, Alessandra, Magnani, Mauro, Hiscott, John, De Chiara, Giovanna, Palamara, Anna Teresa, Nencioni, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770543/ https://www.ncbi.nlm.nih.gov/pubmed/35071051 http://dx.doi.org/10.3389/fcimb.2021.804976 |
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