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Quantification of bone marrow interstitial pH and calcium concentration by intravital ratiometric imaging
The fate of hematopoietic stem cells (HSCs) can be directed by microenvironmental factors including extracellular calcium ion concentration ([Ca(2+)](e)), but the local [Ca(2+)](e) around individual HSCs in vivo remains unknown. Here we develop intravital ratiometric analyses to quantify the absolut...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770570/ https://www.ncbi.nlm.nih.gov/pubmed/35046411 http://dx.doi.org/10.1038/s41467-022-27973-x |