Cargando…

Anti-miR-135/SPOCK1 axis antagonizes the influence of metabolism on drug response in intestinal/colon tumour organoids

Little is known about the role of microRNAs (miRNAs) in rewiring the metabolism within tumours and adjacent non-tumour bearing normal tissue and their potential in cancer therapy. This study aimed to investigate the relationship between deregulated miRNAs and metabolic components in murine duodenal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Babaei-Jadidi, Roya, Kashfi, Hossein, Alelwani, Walla, Karimi Bakhtiari, Ashkan, Kattan, Shahad W., Mansouri, Omniah A., Mukherjee, Abhik, Lobo, Dileep N., Nateri, Abdolrahman S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770633/ https://www.ncbi.nlm.nih.gov/pubmed/35046388 http://dx.doi.org/10.1038/s41389-021-00376-1

Ejemplares similares

Fbxw7-associated drug resistance is reversed by induction of terminal differentiation in murine intestinal organoid culture
por: Lorenzi, Federica, et al.
Publicado: (2016)

Repurposing Antibacterial AM404 As a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells
por: Ahmed, Mehreen, et al.
Publicado: (2019)

FLYWCH1, a Multi-Functional Zinc Finger Protein Contributes to the DNA Repair Pathway
por: Almozyan, Sheema, et al.
Publicado: (2021)

Morphological alterations of cultured human colorectal matched tumour and healthy organoids
por: Kashfi, Seyed Mohammad Hossein, et al.
Publicado: (2018)

Green-synthesized nanoparticles of the polyherbal extract attenuate the necrosis of pancreatic β-cell in a streptozotocin-induced diabetic model
por: Hasan Chowdhury, Muhammad Abid, et al.
Publicado: (2023)

FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15
por: Li, Ningning, et al.
Publicado: (2015)

Increased FLYWCH1 Expression is Negatively Correlated with Wnt/β-catenin Target Gene Expression in Acute Myeloid Leukemia Cells
por: Almars, Amany, et al.
Publicado: (2019)

ATM Regulated PTEN Degradation Is XIAP E3 Ubiquitin Ligase Mediated in p85α Deficient Cancer Cells and Influence Platinum Sensitivity
por: Ali, Reem, et al.
Publicado: (2019)

Java testing with Spock
por: Kapelonis, Konstantinos
Publicado: (2016)

Spock, 'frito' en segundos
Publicado: (2010)

MicroRNA-499a (rs3746444A/G) gene variant and susceptibility to type 2 diabetes-associated end-stage renal disease
por: Fawzy, Manal S., et al.
Publicado: (2022)

Complete Genome of Bacillus thuringiensis Myophage Spock
por: Maroun, Justin W., et al.
Publicado: (2013)

SPOCK1 Promotes the Development of Hepatocellular Carcinoma
por: Váncza, Lóránd, et al.
Publicado: (2022)

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation
por: Babaei-Jadidi, Roya, et al.
Publicado: (2011)

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance
por: Li, Ningning, et al.
Publicado: (2019)

Corrigendum: SPOCK1 promotes the development of hepatocellular carcinoma
por: Váncza, Lóránd, et al.
Publicado: (2023)

Understanding cell‐cell communication and signaling in the colorectal cancer microenvironment
por: AlMusawi, Shaikha, et al.
Publicado: (2021)

Spock, up and running: writing expressive tests in Java and Groovy
por: Fletcher, Rob
Publicado: (2017)

Stromal SPOCK1 supports invasive pancreatic cancer growth
por: Veenstra, Veronique L., et al.
Publicado: (2017)

SPOCK1 Overexpression Suggests Poor Prognosis of Ovarian Cancer
por: Váncza, Lóránd, et al.
Publicado: (2023)

Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches
por: Onyido, Emenike K., et al.
Publicado: (2016)

Spheroid-Formation (Colonosphere) Assay for in Vitro Assessment and Expansion of Stem Cells in Colon Cancer
por: Shaheen, Sameerah, et al.
Publicado: (2016)

Tensin4 (TNS4) is upregulated by Wnt signalling in adenomas in multiple intestinal neoplasia (Min) mice
por: Raposo, Teresa P., et al.
Publicado: (2020)

SPOCK1 Overexpression Confers a Poor Prognosis in Urothelial Carcinoma
por: Ma, Li-Jung, et al.
Publicado: (2016)

SPOCK1 promotes tumor growth and metastasis in human prostate cancer
por: Chen, Qi, et al.
Publicado: (2016)

Multiomic analysis of the function of SPOCK1 across cancers: an integrated bioinformatics approach
por: Han, Jie, et al.
Publicado: (2021)

SPOCK1 Involvement in Epithelial-to-Mesenchymal Transition: A New Target in Cancer Therapy?
por: Sun, Li-rui, et al.
Publicado: (2020)

High SPOCK1 Expression Is Associated with Advanced Stage, T Value, and Gleason Grade in Prostate Cancer
por: Chen, Mei-Ling, et al.
Publicado: (2019)

SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth
por: Alshargabi, Rehab, et al.
Publicado: (2020)

SPOCK2 Serves as a Potential Prognostic Marker and Correlates With Immune Infiltration in Lung Adenocarcinoma
por: Zhao, Jinming, et al.
Publicado: (2020)

Expression and Potential Prognostic Value of SOX9, MCL-1 and SPOCK1 in Gastric Adenocarcinoma
por: Luo, Wenyi, et al.
Publicado: (2022)

Clinical significance of SPOCK2 expression signature for high-grade serous ovarian cancer patients
por: Jiao, Mi, et al.
Publicado: (2022)

SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor immune infiltrates in colorectal cancer
por: Gan, Caiqin, et al.
Publicado: (2023)

Genome-Wide Association Analyses Identify SPOCK as a Key Novel Gene Underlying Age at Menarche
por: Liu, Yao-Zhong, et al.
Publicado: (2009)

SPOCK1 promotes the invasion and metastasis of gastric cancer through Slug‐induced epithelial‐mesenchymal transition
por: Chen, Dehu, et al.
Publicado: (2017)

Network-based identification of signature genes KLF6 and SPOCK1 associated with oral submucous fibrosis
por: Singh, Prithvi, et al.
Publicado: (2020)

Assessment of the prognostic value of SPOCK1 in clear cell renal cell carcinoma: a bioinformatics analysis
por: Chen, Jie, et al.
Publicado: (2022)

Mechanism of prognostic marker SPOCK3 affecting malignant progression of prostate cancer and construction of prognostic model
por: Luo, Jiawen, et al.
Publicado: (2023)

EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth
por: Perurena, Naiara, et al.
Publicado: (2017)

MicroRNA-155-5p inhibits the invasion and migration of prostate cancer cells by targeting SPOCK1
por: Yao, Lin-Ya, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2nsejpa1sifpm2u8l2ik1mtgkf