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Endoplasmic reticulum stress contributes to the decline in doublecortin expression in the immature neurons of mice with long-term obesity

Adult hippocampal neurogenesis (AHN) plays an important role in hippocampus-dependent function. The number of doublecortin (Dcx)-positive immature neurons in the dentate gyrus decreases over time, especially in the early stages of Alzheimer’s disease (AD), and is further reduced in later stages of A...

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Detalles Bibliográficos
Autores principales: Nakagawa, Kiyomi, Islam, Saiful, Ueda, Masashi, Nakagawa, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770636/
https://www.ncbi.nlm.nih.gov/pubmed/35046482
http://dx.doi.org/10.1038/s41598-022-05012-5

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