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STAT6 contributes to renal fibrosis by modulating PPARα-mediated tubular fatty acid oxidation

Lipid metabolism, especially fatty acid oxidation (FAO) dysfunction, is a major driver of renal fibrosis; however, the detailed regulatory mechanisms involved remain unclear. In this study, we showed that there existed an association between the signal transducer and activator of transcription 6 (ST...

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Detalles Bibliográficos
Autores principales: Li, Jianzhong, Yang, Youjing, Li, Qianmin, Wei, Shuhui, Zhou, Yujia, Yu, Wangjianfei, Xue, Lian, Zhou, Ling, Shen, Lei, Lu, Guoyuan, Chen, Ling, Tao, Shasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770798/
https://www.ncbi.nlm.nih.gov/pubmed/35046382
http://dx.doi.org/10.1038/s41419-022-04515-3