A Murine Model of X-Linked Moesin-Associated Immunodeficiency (X-MAID) Reveals Defects in T Cell Homeostasis and Migration

X-linked moesin associated immunodeficiency (X-MAID) is a primary immunodeficiency disease in which patients suffer from profound lymphopenia leading to recurrent infections. The disease is caused by a single point mutation leading to a R171W amino acid change in the protein moesin (moesin(R171W))....

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Detalles Bibliográficos
Autores principales: Avery, Lyndsay, Robertson, Tanner F., Wu, Christine F., Roy, Nathan H., Chauvin, Samuel D., Perkey, Eric, Vanderbeck, Ashley, Maillard, Ivan, Burkhardt, Janis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8770857/
https://www.ncbi.nlm.nih.gov/pubmed/35069520
http://dx.doi.org/10.3389/fimmu.2021.726406

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