Comparison of statistical methods for the analysis of recurrent adverse events in the presence of non-proportional hazards and unobserved heterogeneity: a simulation study

BACKGROUND: In preventive drug trials such as intermittent preventive treatment for malaria prevention during pregnancy (IPTp), where there is repeated treatment administration, recurrence of adverse events (AEs) is expected. Challenges in modelling the risk of the AEs include accounting for time-to...

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Detalles Bibliográficos
Autores principales: Patson, Noel, Mukaka, Mavuto, Kazembe, Lawrence, Eijkemans, Marinus J. C., Mathanga, Don, Laufer, Miriam K., Chirwa, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771190/
https://www.ncbi.nlm.nih.gov/pubmed/35057743
http://dx.doi.org/10.1186/s12874-021-01475-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771190/
https://www.ncbi.nlm.nih.gov/pubmed/35057743
http://dx.doi.org/10.1186/s12874-021-01475-8

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