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Intervertebral bridging ossification after kyphoplasty in a Parkinson’s patient with Kummell’s disease: A case report

BACKGROUND: The short-term therapeutic efficacy of kyphoplasty on Kummell’s disease is obvious. However, postoperative refracture and adjacent vertebral fracture occur occasionally and are difficult to treat. Parkinson's disease (PD) is a pathological disorder associated with heterotopic ossifi...

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Autores principales: Li, Jie, Liu, Yun, Peng, Lei, Liu, Jian, Cao, Zhi-Dong, He, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771369/
https://www.ncbi.nlm.nih.gov/pubmed/35097094
http://dx.doi.org/10.12998/wjcc.v10.i2.677
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author Li, Jie
Liu, Yun
Peng, Lei
Liu, Jian
Cao, Zhi-Dong
He, Miao
author_facet Li, Jie
Liu, Yun
Peng, Lei
Liu, Jian
Cao, Zhi-Dong
He, Miao
author_sort Li, Jie
collection PubMed
description BACKGROUND: The short-term therapeutic efficacy of kyphoplasty on Kummell’s disease is obvious. However, postoperative refracture and adjacent vertebral fracture occur occasionally and are difficult to treat. Parkinson's disease (PD) is a pathological disorder associated with heterotopic ossification. In a patient with PD, an intervertebral bridge was formed in a short period of time after postoperative refracture and adjacent vertebral fracture, providing new stability. CASE SUMMARY: A 78-year-old woman had been suffering from PD for more than 10 years. Three months before operation, she developed lower back pain and discomfort. The visual analog scale (VAS) score was 9 points. Preoperative magnetic resonance imaging indicated collapse of the L2 vertebra. Kyphoplasty was performed and significantly decreased the severity of intractable pain. The patient’s VAS score for pain improved from 9 to 2. Fifty days postoperatively, the patient suddenly developed severe back pain, and the VAS score was 9 points. X-ray showed L2 vertebral body collapse, slight forward bone cement displacement, L1 vertebral compression fracture, and severe L1 collapse. The patient was given calcium acetate capsules 0.6 g po qd and alfacalcidol 0.5ug po qd, and bed rest and brace protection were ordered. After conservative treatment for 2 mo, the patient's back pain was alleviated, and the VAS score improved from 9 to 2. Computed tomography at the 7-mo follow-up indicated extensive callus formation around the T12-L2 vertebrae and intervertebral bridging ossification, providing new stability. CONCLUSION: Kyphoplasty is currently a conventional treatment for Kummell's disease, with definite short-term effects. However, complications still occur in the long term, and these complications are difficult to address; thus, the treatment needs to be selected carefully. To avoid refracture, an interlaced structure of bone cement with trabeculae should be created to the greatest extent possible during the injection of bone cement. Surgical intervention may not be urgently needed when a patient with PD experiences refracture and adjacent vertebral fracture, as a strong bridge may help stabilize the vertebrae and relieve pain.
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spelling pubmed-87713692022-01-28 Intervertebral bridging ossification after kyphoplasty in a Parkinson’s patient with Kummell’s disease: A case report Li, Jie Liu, Yun Peng, Lei Liu, Jian Cao, Zhi-Dong He, Miao World J Clin Cases Case Report BACKGROUND: The short-term therapeutic efficacy of kyphoplasty on Kummell’s disease is obvious. However, postoperative refracture and adjacent vertebral fracture occur occasionally and are difficult to treat. Parkinson's disease (PD) is a pathological disorder associated with heterotopic ossification. In a patient with PD, an intervertebral bridge was formed in a short period of time after postoperative refracture and adjacent vertebral fracture, providing new stability. CASE SUMMARY: A 78-year-old woman had been suffering from PD for more than 10 years. Three months before operation, she developed lower back pain and discomfort. The visual analog scale (VAS) score was 9 points. Preoperative magnetic resonance imaging indicated collapse of the L2 vertebra. Kyphoplasty was performed and significantly decreased the severity of intractable pain. The patient’s VAS score for pain improved from 9 to 2. Fifty days postoperatively, the patient suddenly developed severe back pain, and the VAS score was 9 points. X-ray showed L2 vertebral body collapse, slight forward bone cement displacement, L1 vertebral compression fracture, and severe L1 collapse. The patient was given calcium acetate capsules 0.6 g po qd and alfacalcidol 0.5ug po qd, and bed rest and brace protection were ordered. After conservative treatment for 2 mo, the patient's back pain was alleviated, and the VAS score improved from 9 to 2. Computed tomography at the 7-mo follow-up indicated extensive callus formation around the T12-L2 vertebrae and intervertebral bridging ossification, providing new stability. CONCLUSION: Kyphoplasty is currently a conventional treatment for Kummell's disease, with definite short-term effects. However, complications still occur in the long term, and these complications are difficult to address; thus, the treatment needs to be selected carefully. To avoid refracture, an interlaced structure of bone cement with trabeculae should be created to the greatest extent possible during the injection of bone cement. Surgical intervention may not be urgently needed when a patient with PD experiences refracture and adjacent vertebral fracture, as a strong bridge may help stabilize the vertebrae and relieve pain. Baishideng Publishing Group Inc 2022-01-14 2022-01-14 /pmc/articles/PMC8771369/ /pubmed/35097094 http://dx.doi.org/10.12998/wjcc.v10.i2.677 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Case Report
Li, Jie
Liu, Yun
Peng, Lei
Liu, Jian
Cao, Zhi-Dong
He, Miao
Intervertebral bridging ossification after kyphoplasty in a Parkinson’s patient with Kummell’s disease: A case report
title Intervertebral bridging ossification after kyphoplasty in a Parkinson’s patient with Kummell’s disease: A case report
title_full Intervertebral bridging ossification after kyphoplasty in a Parkinson’s patient with Kummell’s disease: A case report
title_fullStr Intervertebral bridging ossification after kyphoplasty in a Parkinson’s patient with Kummell’s disease: A case report
title_full_unstemmed Intervertebral bridging ossification after kyphoplasty in a Parkinson’s patient with Kummell’s disease: A case report
title_short Intervertebral bridging ossification after kyphoplasty in a Parkinson’s patient with Kummell’s disease: A case report
title_sort intervertebral bridging ossification after kyphoplasty in a parkinson’s patient with kummell’s disease: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771369/
https://www.ncbi.nlm.nih.gov/pubmed/35097094
http://dx.doi.org/10.12998/wjcc.v10.i2.677
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