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PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis

PERK is one of the transmembrane sensors of unfolded protein response (UPR) triggered by ER stress. In this study, we evaluated the role of PERK in the sensitivity of hepatocellular carcinoma (HCC) cells to high linear energy transfer (LET) carbon ions (CI). We found that CI irradiation could induce...

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Detalles Bibliográficos
Autores principales:	Zheng, Xiaogang, Liu, Bingtao, Liu, Xiongxiong, Li, Ping, Zhang, Pengcheng, Ye, Fei, Zhao, Ting, Kuang, Yanbei, Chen, Weiqiang, Jin, Xiaodong, Li, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771512/ https://www.ncbi.nlm.nih.gov/pubmed/35069910 http://dx.doi.org/10.7150/jca.61622

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