Bioorthogonal catalytic nanozyme-mediated lysosomal membrane leakage for targeted drug delivery

Rationale: Employing in situ bioorthogonal catalysis within subcellular organelles, such as lysosomes, remains a challenge. Lysosomal membranes pose an intracellular barrier for drug sequestration, thereby greatly limiting drug accumulation and concentrations at intended targets. Here, we provide a...

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Detalles Bibliográficos
Autores principales: Sun, Zhiyuan, Liu, Qiqi, Wang, Xinyue, Wu, Jin, Hu, Xueyan, Liu, Miaomiao, Zhang, Xiangyun, Wei, Yonghua, Liu, Zhijun, Liu, Hongjiang, Chen, Rui, Wang, Fei, Midgley, Adam C., Li, Aitao, Yan, Xiyun, Wang, Yanming, Zhuang, Jie, Huang, Xinglu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771541/
https://www.ncbi.nlm.nih.gov/pubmed/35154478
http://dx.doi.org/10.7150/thno.66325

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