A T-cell independent universal cellular therapy strategy through antigen depletion

Rationale: T cell therapeutic strategy using CD19-targeting chimeric antigen receptor (CAR) is a revolutionary, novel, and successful treatment for B-cell malignancies. However, the dependency on T-cell mediated cytotoxicity restricts CAR-T therapy as a patient-specific individualized therapy with s...

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Detalles Bibliográficos
Autores principales: Li, Dan, Wang, Wenbing, Xie, Shufeng, Ge, Maolin, Wang, Ruiheng, Xu, Qiongyu, Sun, Yan, Zhu, Jiang, Liu, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771543/
https://www.ncbi.nlm.nih.gov/pubmed/35154479
http://dx.doi.org/10.7150/thno.66832

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