Novel insights into the roles and therapeutic implications of MUC1 oncoprotein via regulating proteins and non-coding RNAs in cancer

Mucin 1 (MUC1) is a heterodimeric transmembrane glycoprotein that protects epithelial cells in mammals. The transmembrane C-terminal subunit (MUC1-C) plays a crucial role in oncogenesis. As an oncoprotein, MUC1-C regulates a number of proteins that are associated with tumorigenesis by interacting wi...

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Detalles Bibliográficos
Autores principales: Li, Wei, Han, Yineng, Sun, Chenmin, Li, Xue, Zheng, Junhua, Che, Jianping, Yao, Xudong, Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771546/
https://www.ncbi.nlm.nih.gov/pubmed/35154471
http://dx.doi.org/10.7150/thno.63654

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