Overexpression of MFN2 alleviates sorafenib-induced cardiomyocyte necroptosis via the MAM-CaMKIIδ pathway in vitro and in vivo

Background: The continued success of oncological therapeutics is dependent on the mitigation of treatment-related adverse events, particularly cardiovascular toxicities. As such, there is an important need to understand the basic mechanisms of drug toxicities in the process of antitumor therapy. Our...

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Detalles Bibliográficos
Autores principales: Song, Ziping, Song, Haixu, Liu, Dan, Yan, Bing, Wang, Daowen, Zhang, Yan, Zhao, Xiaojie, Tian, Xiaoxiang, Yan, Chenghui, Han, Yaling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771548/
https://www.ncbi.nlm.nih.gov/pubmed/35154486
http://dx.doi.org/10.7150/thno.65716

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