Cargando…

Macropinocytic dextran facilitates KRAS-targeted delivery while reducing drug-induced tumor immunity depletion in pancreatic cancer

Background: Pancreatic cancer comprises not only cancer cells but also a collection of cross-talking noncancerous cells within tumor. Therefore, selective delivery of cytotoxic agents towards cancer cells and limiting the collateral damage to tumor suppressive benign cells, such as effector lymphocy...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Fang, Sun, Mengnan, Liu, Zhengsheng, Liu, Huiqin, Kong, Weijian, Wang, Rui, Qian, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771557/
https://www.ncbi.nlm.nih.gov/pubmed/35154474
http://dx.doi.org/10.7150/thno.65299