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Macropinocytic dextran facilitates KRAS-targeted delivery while reducing drug-induced tumor immunity depletion in pancreatic cancer

Background: Pancreatic cancer comprises not only cancer cells but also a collection of cross-talking noncancerous cells within tumor. Therefore, selective delivery of cytotoxic agents towards cancer cells and limiting the collateral damage to tumor suppressive benign cells, such as effector lymphocy...

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Detalles Bibliográficos
Autores principales:	Yuan, Fang, Sun, Mengnan, Liu, Zhengsheng, Liu, Huiqin, Kong, Weijian, Wang, Rui, Qian, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771557/ https://www.ncbi.nlm.nih.gov/pubmed/35154474 http://dx.doi.org/10.7150/thno.65299

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