Cargando…

Overexpression of BACH1 mediated by IGF2 facilitates hepatocellular carcinoma growth and metastasis via IGF1R and PTK2

Background: Accumulating studies manifest that BTB and CNC homology 1 (BACH1) facilitates multiple malignancies progression and metastasis, and targeting the BACH1 pathway enhances antitumor efficacy. Nevertheless, the exact mechanism of BACH1 promoting growth and metastasis and its therapeutic sign...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Meng, Sun, Mengyu, Ji, Xiaoyu, Li, Dongxiao, Chen, Xiaoping, Zhang, Bixiang, Huang, Wenjie, Zhang, Tongyue, Wang, Yijun, Tian, Dean, Xia, Limin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771560/ https://www.ncbi.nlm.nih.gov/pubmed/35154476 http://dx.doi.org/10.7150/thno.65775

Ejemplares similares

HGF-mediated elevation of ETV1 facilitates hepatocellular carcinoma metastasis through upregulating PTK2 and c-MET
por: Zhang, Tongyue, et al.
Publicado: (2022)

IGF1-mediated HOXA13 overexpression promotes colorectal cancer metastasis through upregulating ACLY and IGF1R
por: Qiao, Chenyang, et al.
Publicado: (2021)

ONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY
por: Liu, Danfei, et al.
Publicado: (2021)

Correction to: ONECUT2 facilitates hepatocellular carcinoma metastasis by transcriptionally upregulating FGF2 and ACLY
por: Liu, Danfei, et al.
Publicado: (2021)

HMGB1-mediated elevation of KLF7 facilitates hepatocellular carcinoma progression and metastasis through upregulating TLR4 and PTK2
por: Feng, Weibo, et al.
Publicado: (2023)

PTK6 Regulates IGF-1-Induced Anchorage-Independent Survival
por: Irie, Hanna Y., et al.
Publicado: (2010)

HNRNPC downregulation inhibits IL‐6/STAT3‐mediated HCC metastasis by decreasing HIF1A expression
por: Liu, Danfei, et al.
Publicado: (2022)

CXCL12-mediated HOXB5 overexpression facilitates Colorectal Cancer metastasis through transactivating CXCR4 and ITGB3
por: Feng, Weibo, et al.
Publicado: (2021)

Overexpression of IGF2 affects mouse weight and glycolipid metabolism and IGF2 is positively related to macrosomia
por: Zhang, Qidi, et al.
Publicado: (2023)

FOXC1 promotes HCC proliferation and metastasis by Upregulating DNMT3B to induce DNA Hypermethylation of CTH promoter
por: Lin, Zhuoying, et al.
Publicado: (2021)

Associations among IGF-1, IGF2, IGF-1R, IGF-2R, IGFBP-3, insulin genetic polymorphisms and central precocious puberty in girls
por: Chang, Hua-Pin, et al.
Publicado: (2018)

IGF-1 facilitates extinction of conditioned fear
por: Maglio, Laura E, et al.
Publicado: (2021)

Overexpression of IGF2 and IGF2 receptor in malignant solitary fibrous tumor with hypoglycemia: a case report
por: Arakawa, Yusuke, et al.
Publicado: (2018)

Sequential activation of uterine epithelial IGF1R by stromal IGF1 and embryonic IGF2 directs normal uterine preparation for embryo implantation
por: Zhou, Chan, et al.
Publicado: (2021)

IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
por: Yoneyama, Yosuke, et al.
Publicado: (2018)

A Novel Signature Constructed by Immune-Related LncRNA Predicts the Immune Landscape of Colorectal Cancer
por: Sun, Mengyu, et al.
Publicado: (2021)

Therapeutic Values of Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma: Facts and Hopes
por: Wang, Yijun, et al.
Publicado: (2021)

Homeobox B5 promotes metastasis and poor prognosis in Hepatocellular Carcinoma, via FGFR4 and CXCL1 upregulation
por: He, Qin, et al.
Publicado: (2021)

IGF2 and IGF1R mRNAs Are Detectable in Human Spermatozoa
por: Cannarella, Rossella, et al.
Publicado: (2020)

The IGF1 P2 promoter is an epigenetic QTL for circulating IGF1 and human growth
por: Ouni, Meriem, et al.
Publicado: (2015)

Circulating IGF1 and IGF2 and SNP genotypes in men and pregnant and non-pregnant women
por: Gatford, K L, et al.
Publicado: (2014)

Advance of SOX Transcription Factors in Hepatocellular Carcinoma: From Role, Tumor Immune Relevance to Targeted Therapy
por: Luo, Xiangyuan, et al.
Publicado: (2022)

m(6)A Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization in Pancreatic Cancer
por: Sun, Mengyu, et al.
Publicado: (2021)

TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1
por: Choi, Soo-Im, et al.
Publicado: (2014)

Mechanical Stress-Induced IGF-1 Facilitates col-I and col-III Synthesis via the IGF-1R/AKT/mTORC1 Signaling Pathway
por: Yan, Bin, et al.
Publicado: (2021)

Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells
por: Tominaga, K, et al.
Publicado: (2017)

Yak IGF2 Promotes Fibroblast Proliferation Via Suppression of IGF1R and PI3KCG Expression
por: Zhang, Quanwei, et al.
Publicado: (2018)

Interaction between IGF-IR and ER Induced by E2 and IGF-I
por: Yu, Zhenghong, et al.
Publicado: (2013)

Does Reduced IGF-1R Signaling in Igf1r (+/−) Mice Alter Aging?
por: Bokov, Alex F., et al.
Publicado: (2011)

The IGF2/IGF1R/Nanog Signaling Pathway Regulates the Proliferation of Acute Myeloid Leukemia Stem Cells
por: Xu, Dan-dan, et al.
Publicado: (2018)

Matrix metalloproteinase‐1 facilitates MSC migration via cleavage of IGF‐2/IGFBP2 complex
por: Guan, Shou P., et al.
Publicado: (2017)

Autocrine IGF-1 Action in Adipocytes Controls Systemic IGF-1 Concentrations and Growth
por: Klöting, Nora, et al.
Publicado: (2008)

IGF/IGF-1R signal pathway in pain: a promising therapeutic target
por: Ma, Lulin, et al.
Publicado: (2023)

Relationship of porcine IGF2 imprinting status to DNA methylation at the H19 DMD and the IGF2 DMRs 1 and 2
por: Braunschweig, Martin H, et al.
Publicado: (2011)

Different Epigenetic Alterations Are Associated with Abnormal IGF2/Igf2 Upregulation in Neural Tube Defects
por: Bai, Baoling, et al.
Publicado: (2014)

Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators
por: Suh, Hyeon-Sook, et al.
Publicado: (2013)

Looking at IGF-1 through the hourglass
por: Zhang, William B., et al.
Publicado: (2022)

Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2
por: Potalitsyn, Pavlo, et al.
Publicado: (2023)

Pan-Cancer Analysis of IGF-1 and IGF-1R as Potential Prognostic Biomarkers and Immunotherapy Targets
por: Zhang, Yinqi, et al.
Publicado: (2021)

Relation of the IGF/IGF1R system to autophagy in colitis and colorectal cancer
por: Sipos, Ferenc, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_bga55k7datv6t457cqdtp35cqi