Downregulation of low-density lipoprotein receptor mRNA in lymphatic endothelial cells impairs lymphatic function through changes in intracellular lipids

Rationale: Impairment in lymphatic transport is associated with the onset and progression of atherosclerosis in animal models. The downregulation of low-density-lipoprotein receptor (LDLR) expression, rather than increased circulating cholesterol level per se, is involved in early atherosclerosis-re...

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Detalles Bibliográficos
Autores principales: Vachon, Laurent, Smaani, Ali, Tessier, Nolwenn, Jean, Gabriel, Demers, Annie, Milasan, Andreea, Ardo, Nadine, Jarry, Stéphanie, Villeneuve, Louis, Alikashani, Azadeh, Finherty, Vincent, Ruiz, Matthieu, Sorci-Thomas, Mary G., Mayer, Gaétan, Martel, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771568/
https://www.ncbi.nlm.nih.gov/pubmed/35154499
http://dx.doi.org/10.7150/thno.58780

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