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Comparative Analysis of Antibodies and Heavily Glycosylated Macromolecular Immune Complexes by Size-Exclusion Chromatography Multi-Angle Light Scattering, Native Charge Detection Mass Spectrometry, and Mass Photometry
[Image: see text] Qualitative and quantitative mass analysis of antibodies and related macromolecular immune complexes is a prerequisite for determining their identity, binding partners, stoichiometries, and affinities. A plethora of bioanalytical technologies exist to determine such characteristics...
Autores principales: | den Boer, Maurits A., Lai, Szu-Hsueh, Xue, Xiaoguang, van Kampen, Muriel D., Bleijlevens, Boris, Heck, Albert J. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771642/ https://www.ncbi.nlm.nih.gov/pubmed/34939405 http://dx.doi.org/10.1021/acs.analchem.1c03656 |
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