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Comparative Analysis of Antibodies and Heavily Glycosylated Macromolecular Immune Complexes by Size-Exclusion Chromatography Multi-Angle Light Scattering, Native Charge Detection Mass Spectrometry, and Mass Photometry

[Image: see text] Qualitative and quantitative mass analysis of antibodies and related macromolecular immune complexes is a prerequisite for determining their identity, binding partners, stoichiometries, and affinities. A plethora of bioanalytical technologies exist to determine such characteristics...

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Detalles Bibliográficos
Autores principales: den Boer, Maurits A., Lai, Szu-Hsueh, Xue, Xiaoguang, van Kampen, Muriel D., Bleijlevens, Boris, Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771642/
https://www.ncbi.nlm.nih.gov/pubmed/34939405
http://dx.doi.org/10.1021/acs.analchem.1c03656

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