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Psychopathology and cognitive deficits in young people exposed to complex trauma

AIMS: Complex traumas are traumatic experiences that involve multiple interpersonal threats during childhood or adolescence, such as repeated abuse. This type of trauma is hypothesized to lead to more severe psychopathology and poorer cognitive function than other non-complex traumas, such as road t...

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Autores principales: Lewis, Stephanie J, Koenen, Karestan C, Ambler, Antony, Arseneault, Louise, Caspi, Avshalom, Fisher, Helen L, Moffitt, Terrie E, Danese, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771868/
http://dx.doi.org/10.1192/bjo.2021.149
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author Lewis, Stephanie J
Koenen, Karestan C
Ambler, Antony
Arseneault, Louise
Caspi, Avshalom
Fisher, Helen L
Moffitt, Terrie E
Danese, Andrea
author_facet Lewis, Stephanie J
Koenen, Karestan C
Ambler, Antony
Arseneault, Louise
Caspi, Avshalom
Fisher, Helen L
Moffitt, Terrie E
Danese, Andrea
author_sort Lewis, Stephanie J
collection PubMed
description AIMS: Complex traumas are traumatic experiences that involve multiple interpersonal threats during childhood or adolescence, such as repeated abuse. This type of trauma is hypothesized to lead to more severe psychopathology and poorer cognitive function than other non-complex traumas, such as road traffic accidents. However, empirical testing of this hypothesis has been limited to clinical or convenience samples and cross-sectional designs. To better understand this topic, we aimed to investigate psychopathology and cognitive function in young people exposed to complex, non-complex, or no trauma from a population-representative longitudinal cohort, and to consider the role of pre-existing vulnerabilities. METHOD: Participants were from the Environmental Risk (E-Risk) Longitudinal Twin Study, a population-representative birth-cohort of 2,232 children born in England and Wales in 1994-95. At age 18 years (93% participation), we assessed lifetime exposure to complex and non-complex trauma. We also assessed past-year psychopathology including general psychopathology ‘p’ and several psychiatric disorders, as well as current cognitive function including IQ, executive function, and processing speed. Additionally, we prospectively assessed early childhood vulnerabilities including internalizing and externalizing symptoms at age 5, IQ at age 5, family history of mental illness, family socioeconomic status, and sex. RESULT: We found that participants who had been exposed to complex trauma had more severe psychopathology and poorer cognitive function across wide-ranging measures at age 18, compared to both trauma-unexposed participants and those exposed to non-complex trauma. Early childhood vulnerabilities had an important role in these presentations, as they predicted risk of later complex trauma exposure, and largely explained associations of complex trauma with cognitive deficits, but not with psychopathology. CONCLUSION: By conflating complex and non-complex traumas, current research and clinical practice under-estimate the severity of psychopathology and cognitive deficits linked with complex trauma, as well as the role of pre-existing vulnerabilities. A better understanding of the mental health needs of people exposed to complex trauma and underlying mechanisms could inform the development of new effective interventions.
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spelling pubmed-87718682022-01-31 Psychopathology and cognitive deficits in young people exposed to complex trauma Lewis, Stephanie J Koenen, Karestan C Ambler, Antony Arseneault, Louise Caspi, Avshalom Fisher, Helen L Moffitt, Terrie E Danese, Andrea BJPsych Open Rapid-Fire Poster Presentations AIMS: Complex traumas are traumatic experiences that involve multiple interpersonal threats during childhood or adolescence, such as repeated abuse. This type of trauma is hypothesized to lead to more severe psychopathology and poorer cognitive function than other non-complex traumas, such as road traffic accidents. However, empirical testing of this hypothesis has been limited to clinical or convenience samples and cross-sectional designs. To better understand this topic, we aimed to investigate psychopathology and cognitive function in young people exposed to complex, non-complex, or no trauma from a population-representative longitudinal cohort, and to consider the role of pre-existing vulnerabilities. METHOD: Participants were from the Environmental Risk (E-Risk) Longitudinal Twin Study, a population-representative birth-cohort of 2,232 children born in England and Wales in 1994-95. At age 18 years (93% participation), we assessed lifetime exposure to complex and non-complex trauma. We also assessed past-year psychopathology including general psychopathology ‘p’ and several psychiatric disorders, as well as current cognitive function including IQ, executive function, and processing speed. Additionally, we prospectively assessed early childhood vulnerabilities including internalizing and externalizing symptoms at age 5, IQ at age 5, family history of mental illness, family socioeconomic status, and sex. RESULT: We found that participants who had been exposed to complex trauma had more severe psychopathology and poorer cognitive function across wide-ranging measures at age 18, compared to both trauma-unexposed participants and those exposed to non-complex trauma. Early childhood vulnerabilities had an important role in these presentations, as they predicted risk of later complex trauma exposure, and largely explained associations of complex trauma with cognitive deficits, but not with psychopathology. CONCLUSION: By conflating complex and non-complex traumas, current research and clinical practice under-estimate the severity of psychopathology and cognitive deficits linked with complex trauma, as well as the role of pre-existing vulnerabilities. A better understanding of the mental health needs of people exposed to complex trauma and underlying mechanisms could inform the development of new effective interventions. Cambridge University Press 2021-06-18 /pmc/articles/PMC8771868/ http://dx.doi.org/10.1192/bjo.2021.149 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Rapid-Fire Poster Presentations
Lewis, Stephanie J
Koenen, Karestan C
Ambler, Antony
Arseneault, Louise
Caspi, Avshalom
Fisher, Helen L
Moffitt, Terrie E
Danese, Andrea
Psychopathology and cognitive deficits in young people exposed to complex trauma
title Psychopathology and cognitive deficits in young people exposed to complex trauma
title_full Psychopathology and cognitive deficits in young people exposed to complex trauma
title_fullStr Psychopathology and cognitive deficits in young people exposed to complex trauma
title_full_unstemmed Psychopathology and cognitive deficits in young people exposed to complex trauma
title_short Psychopathology and cognitive deficits in young people exposed to complex trauma
title_sort psychopathology and cognitive deficits in young people exposed to complex trauma
topic Rapid-Fire Poster Presentations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771868/
http://dx.doi.org/10.1192/bjo.2021.149
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