Insect RDL Receptor Models for Virtual Screening: Impact of the Template Conformational State in Pentameric Ligand-Gated Ion Channels

[Image: see text] The RDL receptor is one of the most relevant protein targets for insecticide molecules. It belongs to the pentameric ligand-gated ion channel (pLGIC) family. Given that the experimental structures of pLGICs are difficult to obtain, homology modeling has been extensively used for th...

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Detalles Bibliográficos
Autores principales: Felsztyna, Iván, Villarreal, Marcos A., García, Daniel A., Miguel, Virginia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771969/
https://www.ncbi.nlm.nih.gov/pubmed/35071887
http://dx.doi.org/10.1021/acsomega.1c05465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771969/
https://www.ncbi.nlm.nih.gov/pubmed/35071887
http://dx.doi.org/10.1021/acsomega.1c05465

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