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Insect RDL Receptor Models for Virtual Screening: Impact of the Template Conformational State in Pentameric Ligand-Gated Ion Channels
[Image: see text] The RDL receptor is one of the most relevant protein targets for insecticide molecules. It belongs to the pentameric ligand-gated ion channel (pLGIC) family. Given that the experimental structures of pLGICs are difficult to obtain, homology modeling has been extensively used for th...
Autores principales: | Felsztyna, Iván, Villarreal, Marcos A., García, Daniel A., Miguel, Virginia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8771969/ https://www.ncbi.nlm.nih.gov/pubmed/35071887 http://dx.doi.org/10.1021/acsomega.1c05465 |
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