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Using entropy-driven amplifier circuit response to build nonlinear model under the influence of Lévy jump

BACKGROUND: Bioinformatics is a subject produced by the combination of life science and computer science. It mainly uses computer technology to study the laws of biological systems. The design and realization of DNA circuit reaction is one of the important contents of bioinformatics. RESULTS: In thi...

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Autores principales: Fu, Hao, Lv, Hui, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772049/
https://www.ncbi.nlm.nih.gov/pubmed/35057730
http://dx.doi.org/10.1186/s12859-021-04331-0
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author Fu, Hao
Lv, Hui
Zhang, Qiang
author_facet Fu, Hao
Lv, Hui
Zhang, Qiang
author_sort Fu, Hao
collection PubMed
description BACKGROUND: Bioinformatics is a subject produced by the combination of life science and computer science. It mainly uses computer technology to study the laws of biological systems. The design and realization of DNA circuit reaction is one of the important contents of bioinformatics. RESULTS: In this paper, nonlinear dynamic system model with Lévy jump based on entropy-driven amplifier (EDA) circuit response is studied. Firstly, nonlinear biochemical reaction system model is established based on EDA circuit response. Considering the influence of disturbance factors on the system, nonlinear biochemical reaction system with Lévy jump is built. Secondly, in order to prove that the constructed system conforms to the actual meaning, the existence and uniqueness of the system solution is analyzed. Next, the sufficient conditions for the end and continuation of EDA circuit reaction are certified. Finally, the correctness of the theoretical results is proved by numerical simulation, and the reactivity of THTSignal in EDA circuit under different noise intensity is verified. CONCLUSIONS: In EDA circuit reaction, the intensity of external noise has a significant impact on the system. The end of EDA circuit reaction is closely related to the intensity of Lévy noise, and Lévy jump has a significant impact on the nature of biochemical reaction system.
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spelling pubmed-87720492022-01-20 Using entropy-driven amplifier circuit response to build nonlinear model under the influence of Lévy jump Fu, Hao Lv, Hui Zhang, Qiang BMC Bioinformatics Research BACKGROUND: Bioinformatics is a subject produced by the combination of life science and computer science. It mainly uses computer technology to study the laws of biological systems. The design and realization of DNA circuit reaction is one of the important contents of bioinformatics. RESULTS: In this paper, nonlinear dynamic system model with Lévy jump based on entropy-driven amplifier (EDA) circuit response is studied. Firstly, nonlinear biochemical reaction system model is established based on EDA circuit response. Considering the influence of disturbance factors on the system, nonlinear biochemical reaction system with Lévy jump is built. Secondly, in order to prove that the constructed system conforms to the actual meaning, the existence and uniqueness of the system solution is analyzed. Next, the sufficient conditions for the end and continuation of EDA circuit reaction are certified. Finally, the correctness of the theoretical results is proved by numerical simulation, and the reactivity of THTSignal in EDA circuit under different noise intensity is verified. CONCLUSIONS: In EDA circuit reaction, the intensity of external noise has a significant impact on the system. The end of EDA circuit reaction is closely related to the intensity of Lévy noise, and Lévy jump has a significant impact on the nature of biochemical reaction system. BioMed Central 2022-01-20 /pmc/articles/PMC8772049/ /pubmed/35057730 http://dx.doi.org/10.1186/s12859-021-04331-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Fu, Hao
Lv, Hui
Zhang, Qiang
Using entropy-driven amplifier circuit response to build nonlinear model under the influence of Lévy jump
title Using entropy-driven amplifier circuit response to build nonlinear model under the influence of Lévy jump
title_full Using entropy-driven amplifier circuit response to build nonlinear model under the influence of Lévy jump
title_fullStr Using entropy-driven amplifier circuit response to build nonlinear model under the influence of Lévy jump
title_full_unstemmed Using entropy-driven amplifier circuit response to build nonlinear model under the influence of Lévy jump
title_short Using entropy-driven amplifier circuit response to build nonlinear model under the influence of Lévy jump
title_sort using entropy-driven amplifier circuit response to build nonlinear model under the influence of lévy jump
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772049/
https://www.ncbi.nlm.nih.gov/pubmed/35057730
http://dx.doi.org/10.1186/s12859-021-04331-0
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