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Extracellular vesicles from adipose-derived stem cells promote microglia M2 polarization and neurological recovery in a mouse model of transient middle cerebral artery occlusion

BACKGROUND: Adipose-derived stem cells (ADSCs) and their extracellular vesicles (EVs) have therapeutic potential in ischemic brain injury, but the underlying mechanism is poorly understood. The current study aimed to explore the contribution of miRNAs in ADSC-EVs to the treatment of cerebral ischemi...

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Detalles Bibliográficos
Autores principales: Hu, Xiaowen, Pan, Jiaji, Li, Yongfang, Jiang, Yixu, Zheng, Haoran, Shi, Rubing, Zhang, Qi, Liu, Chang, Tian, Hengli, Zhang, Zhijun, Tang, Yaohui, Yang, Guo-Yuan, Wang, Yongting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772170/
https://www.ncbi.nlm.nih.gov/pubmed/35057862
http://dx.doi.org/10.1186/s13287-021-02668-0