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Overexpression of PFKFB3 promotes cell glycolysis and proliferation in renal cell carcinoma

BACKGROUND: Cancer cells prefer utilizing aerobic glycolysis in order to exacerbate tumor mass and maintain un-regulated proliferative rates. As a key glycolytic activator, phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) has been implicated in multiple tumor type progression. However,...

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Detalles Bibliográficos
Autores principales:	Li, Jun, Zhang, Shiqiang, Liao, Dingzhun, Zhang, Qian, Chen, Chujie, Yang, Xiangwei, Jiang, Donggen, Pang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772232/ https://www.ncbi.nlm.nih.gov/pubmed/35057732 http://dx.doi.org/10.1186/s12885-022-09183-2

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