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A novel gene functional similarity calculation model by utilizing the specificity of terms and relationships in gene ontology

BACKGROUND: Recently, with the foundation and development of gene ontology (GO) resources, numerous works have been proposed to compute functional similarity of genes and achieved series of successes in some research fields. Focusing on the calculation of the information content (IC) of terms is the...

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Detalles Bibliográficos
Autores principales: Tian, Zhen, Fang, Haichuan, Ye, Yangdong, Zhu, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772239/
https://www.ncbi.nlm.nih.gov/pubmed/35057740
http://dx.doi.org/10.1186/s12859-022-04557-6