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Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China

BACKGROUND: To analyze the health-related quality of life associated with the conversion of dialysis modality among end-stage renal disease patients in China. METHODS: Patients were recruited from hospitals and a dialysis center in Kunshan, China. Patients converting from continuous ambulatory perit...

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Autores principales: Sun, Heqi, Zhuang, Ye, Gao, Lanying, Xu, Ningze, Xiong, Yan, Yuan, Min, Lu, Jun, Ye, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772444/
https://www.ncbi.nlm.nih.gov/pubmed/35111408
http://dx.doi.org/10.7717/peerj.12793
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author Sun, Heqi
Zhuang, Ye
Gao, Lanying
Xu, Ningze
Xiong, Yan
Yuan, Min
Lu, Jun
Ye, Jianming
author_facet Sun, Heqi
Zhuang, Ye
Gao, Lanying
Xu, Ningze
Xiong, Yan
Yuan, Min
Lu, Jun
Ye, Jianming
author_sort Sun, Heqi
collection PubMed
description BACKGROUND: To analyze the health-related quality of life associated with the conversion of dialysis modality among end-stage renal disease patients in China. METHODS: Patients were recruited from hospitals and a dialysis center in Kunshan, China. Patients converting from continuous ambulatory peritoneal dialysis to automated peritoneal dialysis were recruited as the observation group (n = 64), and patients continuing with continuous ambulatory peritoneal dialysis treatment were included in the control group (n = 64) after matching in this retrospective cohort study. Their health-related quality of life was measured using the kidney disease quality of life instrument in 2019 and 2020, respectively. Baseline socio-demographic characteristics and clinical data were collected in 2019. The before-and-after cross-group comparisons of subscale scores of two groups were conducted using a Student‘s t-test. Multiple linear regression models were fitted to identify the factors associated with the change of each scale. RESULTS: The health-related quality of life scores of the two groups was comparable in baseline, while the observation group had higher scores in Physical Component Summary (51.92 ± 7.50), Kidney Disease Component Summary (81.21 ± 8.41), Symptoms (90.76 ± 6.30), Effects (82.86 ± 11.42), and Burden (69.04 ± 15.69) subscales after one year. In multivariate regression analysis, the change of Physical Component Summary was significantly associated with conversion to APD (β = 11.54, 95% CI [7.26–15.82]); the change of Mental Component Summary with higher education (β =  − 5.96, 95% CI [−10.18–−1.74]) and CCI (>2) (β = 5.39, 95% CI [1.05–9.73]); the change of Kidney Disease Component Summary with conversion to APD (β = 15.95, 95% CI [10.19–21.7]) and age (>60 years) (β =  − 7.36, 95% CI [−14.11–−0.61]); the change of Symptoms with CCI (>2) (β = 7.96, 95% CI [1.49–14.44]); the change of Effects with conversion to APD (β = 19.23, 95% CI [11.57–26.88]); and the change of Burden with conversion to APD (β = 22.40, 95% CI [13.46–31.34]), age (>60 years) (β =  − 12.12, 95% CI [−22.59–−1.65]), and higher education (β =  − 10.38, 95% CI [−19.79–−0.98]). CONCLUSIONS: The conversion of dialysis modality had a significant impact on the scores of most subscales. Patients converting from continuous ambulatory peritoneal dialysis to automated peritoneal dialysis generally had improved health-related quality of life scores.
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spelling pubmed-87724442022-02-01 Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China Sun, Heqi Zhuang, Ye Gao, Lanying Xu, Ningze Xiong, Yan Yuan, Min Lu, Jun Ye, Jianming PeerJ Global Health BACKGROUND: To analyze the health-related quality of life associated with the conversion of dialysis modality among end-stage renal disease patients in China. METHODS: Patients were recruited from hospitals and a dialysis center in Kunshan, China. Patients converting from continuous ambulatory peritoneal dialysis to automated peritoneal dialysis were recruited as the observation group (n = 64), and patients continuing with continuous ambulatory peritoneal dialysis treatment were included in the control group (n = 64) after matching in this retrospective cohort study. Their health-related quality of life was measured using the kidney disease quality of life instrument in 2019 and 2020, respectively. Baseline socio-demographic characteristics and clinical data were collected in 2019. The before-and-after cross-group comparisons of subscale scores of two groups were conducted using a Student‘s t-test. Multiple linear regression models were fitted to identify the factors associated with the change of each scale. RESULTS: The health-related quality of life scores of the two groups was comparable in baseline, while the observation group had higher scores in Physical Component Summary (51.92 ± 7.50), Kidney Disease Component Summary (81.21 ± 8.41), Symptoms (90.76 ± 6.30), Effects (82.86 ± 11.42), and Burden (69.04 ± 15.69) subscales after one year. In multivariate regression analysis, the change of Physical Component Summary was significantly associated with conversion to APD (β = 11.54, 95% CI [7.26–15.82]); the change of Mental Component Summary with higher education (β =  − 5.96, 95% CI [−10.18–−1.74]) and CCI (>2) (β = 5.39, 95% CI [1.05–9.73]); the change of Kidney Disease Component Summary with conversion to APD (β = 15.95, 95% CI [10.19–21.7]) and age (>60 years) (β =  − 7.36, 95% CI [−14.11–−0.61]); the change of Symptoms with CCI (>2) (β = 7.96, 95% CI [1.49–14.44]); the change of Effects with conversion to APD (β = 19.23, 95% CI [11.57–26.88]); and the change of Burden with conversion to APD (β = 22.40, 95% CI [13.46–31.34]), age (>60 years) (β =  − 12.12, 95% CI [−22.59–−1.65]), and higher education (β =  − 10.38, 95% CI [−19.79–−0.98]). CONCLUSIONS: The conversion of dialysis modality had a significant impact on the scores of most subscales. Patients converting from continuous ambulatory peritoneal dialysis to automated peritoneal dialysis generally had improved health-related quality of life scores. PeerJ Inc. 2022-01-17 /pmc/articles/PMC8772444/ /pubmed/35111408 http://dx.doi.org/10.7717/peerj.12793 Text en ©2022 Sun et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Global Health
Sun, Heqi
Zhuang, Ye
Gao, Lanying
Xu, Ningze
Xiong, Yan
Yuan, Min
Lu, Jun
Ye, Jianming
Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China
title Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China
title_full Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China
title_fullStr Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China
title_full_unstemmed Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China
title_short Impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in China
title_sort impact of dialysis modality conversion on the health-related quality of life of peritoneal dialysis patients: a retrospective cohort study in china
topic Global Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772444/
https://www.ncbi.nlm.nih.gov/pubmed/35111408
http://dx.doi.org/10.7717/peerj.12793
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