Cargando…

Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus: A case report

RATIONALE: Renal cell carcinoma (RCC) is the most common type of kidney cancer and is the second most common urologic neoplasm. Vaginal metastasis from RCC is extremely rare clinically. PATIENT CONCERNS: A 56-year-old woman presented with intermittent vaginal bleeding that had persisted for 1 month....

Descripción completa

Detalles Bibliográficos
Autores principales: Geng, Zhihai, Zhang, Qinghua, Jia, Peng, Miao, Jia, Lin, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772633/
https://www.ncbi.nlm.nih.gov/pubmed/35060522
http://dx.doi.org/10.1097/MD.0000000000028586
_version_ 1784635887790850048
author Geng, Zhihai
Zhang, Qinghua
Jia, Peng
Miao, Jia
Lin, Qian
author_facet Geng, Zhihai
Zhang, Qinghua
Jia, Peng
Miao, Jia
Lin, Qian
author_sort Geng, Zhihai
collection PubMed
description RATIONALE: Renal cell carcinoma (RCC) is the most common type of kidney cancer and is the second most common urologic neoplasm. Vaginal metastasis from RCC is extremely rare clinically. PATIENT CONCERNS: A 56-year-old woman presented with intermittent vaginal bleeding that had persisted for 1 month. Enhanced computed tomography examination suggested a vaginal mass (3 × 2 × 2 cm), right kidney tumor (15 × 12 × 10 cm), and an inferior vena cava tumor thrombus. During gynecologic examination, the mass was necrotic and caused uncontrollable vaginal bleeding. DIAGNOSES: Based on clinical and imaging examinations and the pathology, she was diagnosed as vaginal metastasis from RCC. INTERVENTIONS: The patient received percutaneous transcatheter arterial embolization to stop uncontrollable vaginal bleeding, and then treated with targeted therapy. OUTCOMES: Vaginal bleeding disappeared after interventional embotherapy. However, disease progressed, and the patient died 9 months later. LESSONS: In cases of vaginal bleeding, the possibility of metastatic renal cell carcinoma should be considered. Percutaneous transcatheter arterial embolization is an effective and novel treatment for uncontrollable vaginal bleeding caused by vaginal metastasis of RCC.
format Online
Article
Text
id pubmed-8772633
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-87726332022-01-21 Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus: A case report Geng, Zhihai Zhang, Qinghua Jia, Peng Miao, Jia Lin, Qian Medicine (Baltimore) 7300 RATIONALE: Renal cell carcinoma (RCC) is the most common type of kidney cancer and is the second most common urologic neoplasm. Vaginal metastasis from RCC is extremely rare clinically. PATIENT CONCERNS: A 56-year-old woman presented with intermittent vaginal bleeding that had persisted for 1 month. Enhanced computed tomography examination suggested a vaginal mass (3 × 2 × 2 cm), right kidney tumor (15 × 12 × 10 cm), and an inferior vena cava tumor thrombus. During gynecologic examination, the mass was necrotic and caused uncontrollable vaginal bleeding. DIAGNOSES: Based on clinical and imaging examinations and the pathology, she was diagnosed as vaginal metastasis from RCC. INTERVENTIONS: The patient received percutaneous transcatheter arterial embolization to stop uncontrollable vaginal bleeding, and then treated with targeted therapy. OUTCOMES: Vaginal bleeding disappeared after interventional embotherapy. However, disease progressed, and the patient died 9 months later. LESSONS: In cases of vaginal bleeding, the possibility of metastatic renal cell carcinoma should be considered. Percutaneous transcatheter arterial embolization is an effective and novel treatment for uncontrollable vaginal bleeding caused by vaginal metastasis of RCC. Lippincott Williams & Wilkins 2022-01-21 /pmc/articles/PMC8772633/ /pubmed/35060522 http://dx.doi.org/10.1097/MD.0000000000028586 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle 7300
Geng, Zhihai
Zhang, Qinghua
Jia, Peng
Miao, Jia
Lin, Qian
Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus: A case report
title Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus: A case report
title_full Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus: A case report
title_fullStr Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus: A case report
title_full_unstemmed Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus: A case report
title_short Severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus: A case report
title_sort severe vaginal bleeding due to vaginal metastasis from renal cell carcinoma with inferior vena cava tumor thrombus: a case report
topic 7300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772633/
https://www.ncbi.nlm.nih.gov/pubmed/35060522
http://dx.doi.org/10.1097/MD.0000000000028586
work_keys_str_mv AT gengzhihai severevaginalbleedingduetovaginalmetastasisfromrenalcellcarcinomawithinferiorvenacavatumorthrombusacasereport
AT zhangqinghua severevaginalbleedingduetovaginalmetastasisfromrenalcellcarcinomawithinferiorvenacavatumorthrombusacasereport
AT jiapeng severevaginalbleedingduetovaginalmetastasisfromrenalcellcarcinomawithinferiorvenacavatumorthrombusacasereport
AT miaojia severevaginalbleedingduetovaginalmetastasisfromrenalcellcarcinomawithinferiorvenacavatumorthrombusacasereport
AT linqian severevaginalbleedingduetovaginalmetastasisfromrenalcellcarcinomawithinferiorvenacavatumorthrombusacasereport