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A rare case report of obstructive jaundice caused by mucus-producing cholangiocarcinoma

RATIONALE: Cholangiocarcinoma is a common cause of obstructive jaundice but is mainly associated with solid mass and not semisolid secretion. In this report, the patient was admitted to the hospital with obstructive jaundice; however, no solid mass was found to lead to jaundice. PATIENT CONCERNS: Th...

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Autores principales: Duan, Botao, Zhao, Xuekai, Fan, Songsong, Zhou, Lei, Zhang, Xingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772676/
https://www.ncbi.nlm.nih.gov/pubmed/35060499
http://dx.doi.org/10.1097/MD.0000000000028478
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author Duan, Botao
Zhao, Xuekai
Fan, Songsong
Zhou, Lei
Zhang, Xingyuan
author_facet Duan, Botao
Zhao, Xuekai
Fan, Songsong
Zhou, Lei
Zhang, Xingyuan
author_sort Duan, Botao
collection PubMed
description RATIONALE: Cholangiocarcinoma is a common cause of obstructive jaundice but is mainly associated with solid mass and not semisolid secretion. In this report, the patient was admitted to the hospital with obstructive jaundice; however, no solid mass was found to lead to jaundice. PATIENT CONCERNS: The patient developed symptoms of obstructive jaundice for 10 days, including fatigue and yellow skin staining. DIAGNOSES: Postoperative pathological examination of the bile duct wall revealed cholangioadenocarcinoma, and the jelly like contents were inflammatory secretions. INTERVENTIONS: The patient underwent laparotomy and was diagnosed with obstructive jaundice. An exploratory laparotomy revealed that the content in the biliary duct tree was a jelly like inflammatory secretion. OUTCOMES: Follow-up data revealed that the levels of total bilirubin and aminotransferase were normal, and a computed tomography scan showed no tumor mass. LESSONS: There are very few reports about obstructive jaundice caused by inflammatory secretion that almost filled up the biliary tree. Internal drainage of the cholestatic bile can be achieved through endoscopic retrograde cholangiopancreatograpy, or external drainage can be achieved through percutaneous transhepatic biliary drainage, which can relieve the symptoms of biliary obstruction and improve the patient's quality of life.
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spelling pubmed-87726762022-01-21 A rare case report of obstructive jaundice caused by mucus-producing cholangiocarcinoma Duan, Botao Zhao, Xuekai Fan, Songsong Zhou, Lei Zhang, Xingyuan Medicine (Baltimore) 4500 RATIONALE: Cholangiocarcinoma is a common cause of obstructive jaundice but is mainly associated with solid mass and not semisolid secretion. In this report, the patient was admitted to the hospital with obstructive jaundice; however, no solid mass was found to lead to jaundice. PATIENT CONCERNS: The patient developed symptoms of obstructive jaundice for 10 days, including fatigue and yellow skin staining. DIAGNOSES: Postoperative pathological examination of the bile duct wall revealed cholangioadenocarcinoma, and the jelly like contents were inflammatory secretions. INTERVENTIONS: The patient underwent laparotomy and was diagnosed with obstructive jaundice. An exploratory laparotomy revealed that the content in the biliary duct tree was a jelly like inflammatory secretion. OUTCOMES: Follow-up data revealed that the levels of total bilirubin and aminotransferase were normal, and a computed tomography scan showed no tumor mass. LESSONS: There are very few reports about obstructive jaundice caused by inflammatory secretion that almost filled up the biliary tree. Internal drainage of the cholestatic bile can be achieved through endoscopic retrograde cholangiopancreatograpy, or external drainage can be achieved through percutaneous transhepatic biliary drainage, which can relieve the symptoms of biliary obstruction and improve the patient's quality of life. Lippincott Williams & Wilkins 2022-01-21 /pmc/articles/PMC8772676/ /pubmed/35060499 http://dx.doi.org/10.1097/MD.0000000000028478 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle 4500
Duan, Botao
Zhao, Xuekai
Fan, Songsong
Zhou, Lei
Zhang, Xingyuan
A rare case report of obstructive jaundice caused by mucus-producing cholangiocarcinoma
title A rare case report of obstructive jaundice caused by mucus-producing cholangiocarcinoma
title_full A rare case report of obstructive jaundice caused by mucus-producing cholangiocarcinoma
title_fullStr A rare case report of obstructive jaundice caused by mucus-producing cholangiocarcinoma
title_full_unstemmed A rare case report of obstructive jaundice caused by mucus-producing cholangiocarcinoma
title_short A rare case report of obstructive jaundice caused by mucus-producing cholangiocarcinoma
title_sort rare case report of obstructive jaundice caused by mucus-producing cholangiocarcinoma
topic 4500
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772676/
https://www.ncbi.nlm.nih.gov/pubmed/35060499
http://dx.doi.org/10.1097/MD.0000000000028478
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