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Current Status of Staphylococcal Cassette Chromosome mec (SCCmec)
Staphylococcal cassette chromosome mec (SCCmec) typing was established in the 2000s and has been employed as a tool for the molecular epidemiology of methicillin-resistant Staphylococcus aureus, as well as the evolution investigation of Staphylococcus species. Molecular cloning and the conventional...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772726/ https://www.ncbi.nlm.nih.gov/pubmed/35052963 http://dx.doi.org/10.3390/antibiotics11010086 |
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author | Uehara, Yuki |
author_facet | Uehara, Yuki |
author_sort | Uehara, Yuki |
collection | PubMed |
description | Staphylococcal cassette chromosome mec (SCCmec) typing was established in the 2000s and has been employed as a tool for the molecular epidemiology of methicillin-resistant Staphylococcus aureus, as well as the evolution investigation of Staphylococcus species. Molecular cloning and the conventional sequencing of SCCmec have been adopted to verify the presence and structure of a novel SCCmec type, while convenient PCR-based SCCmec identification methods have been used in practical settings for many years. In addition, whole-genome sequencing has been widely used, and various SCCmec and similar structures have been recently identified in various species. The current status of the SCCmec types, SCCmec subtypes, rules for nomenclature, and multiple methods for identifying SCCmec types and subtypes were summarized in this review, according to the perspective of the International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements. |
format | Online Article Text |
id | pubmed-8772726 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87727262022-01-21 Current Status of Staphylococcal Cassette Chromosome mec (SCCmec) Uehara, Yuki Antibiotics (Basel) Review Staphylococcal cassette chromosome mec (SCCmec) typing was established in the 2000s and has been employed as a tool for the molecular epidemiology of methicillin-resistant Staphylococcus aureus, as well as the evolution investigation of Staphylococcus species. Molecular cloning and the conventional sequencing of SCCmec have been adopted to verify the presence and structure of a novel SCCmec type, while convenient PCR-based SCCmec identification methods have been used in practical settings for many years. In addition, whole-genome sequencing has been widely used, and various SCCmec and similar structures have been recently identified in various species. The current status of the SCCmec types, SCCmec subtypes, rules for nomenclature, and multiple methods for identifying SCCmec types and subtypes were summarized in this review, according to the perspective of the International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements. MDPI 2022-01-11 /pmc/articles/PMC8772726/ /pubmed/35052963 http://dx.doi.org/10.3390/antibiotics11010086 Text en © 2022 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Uehara, Yuki Current Status of Staphylococcal Cassette Chromosome mec (SCCmec) |
title | Current Status of Staphylococcal Cassette Chromosome mec (SCCmec) |
title_full | Current Status of Staphylococcal Cassette Chromosome mec (SCCmec) |
title_fullStr | Current Status of Staphylococcal Cassette Chromosome mec (SCCmec) |
title_full_unstemmed | Current Status of Staphylococcal Cassette Chromosome mec (SCCmec) |
title_short | Current Status of Staphylococcal Cassette Chromosome mec (SCCmec) |
title_sort | current status of staphylococcal cassette chromosome mec (sccmec) |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772726/ https://www.ncbi.nlm.nih.gov/pubmed/35052963 http://dx.doi.org/10.3390/antibiotics11010086 |
work_keys_str_mv | AT ueharayuki currentstatusofstaphylococcalcassettechromosomemecsccmec |