The NRF2-Dependent Transcriptional Regulation of Antioxidant Defense Pathways: Relevance for Cell Type-Specific Vulnerability to Neurodegeneration and Therapeutic Intervention

Oxidative stress has been implicated in the etiology and pathobiology of various neurodegenerative diseases. At baseline, the cells of the nervous system have the capability to regulate the genes for antioxidant defenses by engaging nuclear factor erythroid 2 (NFE2/NRF)-dependent transcriptional mec...

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Detalles Bibliográficos
Autores principales: Boas, Stephanie M., Joyce, Kathlene L., Cowell, Rita M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772787/
https://www.ncbi.nlm.nih.gov/pubmed/35052512
http://dx.doi.org/10.3390/antiox11010008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772787/
https://www.ncbi.nlm.nih.gov/pubmed/35052512
http://dx.doi.org/10.3390/antiox11010008

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