Ceftriaxone for the Treatment of Chronic Bacterial Prostatitis: A Case Series and Literature Review

Chronic bacterial prostatitis is increasingly difficult to treat due to rising antimicrobial resistance limiting oral treatment options. In this case series, 11 men with CBP (including patients with urological comorbidities) due to multi-resistant E. coli were treated with once-daily ceftriaxone int...

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Autores principales: Kuiper, Sander G., Ploeger, Maarten, Wilms, Erik B., van Dijk, Marleen M., Leegwater, Emiel, Huis in’t Veld, Robert A. G., van Nieuwkoop, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772798/
https://www.ncbi.nlm.nih.gov/pubmed/35052960
http://dx.doi.org/10.3390/antibiotics11010083
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author Kuiper, Sander G.
Ploeger, Maarten
Wilms, Erik B.
van Dijk, Marleen M.
Leegwater, Emiel
Huis in’t Veld, Robert A. G.
van Nieuwkoop, Cees
author_facet Kuiper, Sander G.
Ploeger, Maarten
Wilms, Erik B.
van Dijk, Marleen M.
Leegwater, Emiel
Huis in’t Veld, Robert A. G.
van Nieuwkoop, Cees
author_sort Kuiper, Sander G.
collection PubMed
description Chronic bacterial prostatitis is increasingly difficult to treat due to rising antimicrobial resistance limiting oral treatment options. In this case series, 11 men with CBP (including patients with urological comorbidities) due to multi-resistant E. coli were treated with once-daily ceftriaxone intravenously for 6 weeks. Nine patients were clinically cured at 3 months follow up. No early withdrawal of medication due to side effects occurred. A literature review was conducted to describe the prostate pharmacokinetics of ceftriaxone and its use in prostatic infection. In conclusion, ceftriaxone can be considered an appropriate treatment of chronic bacterial prostatitis.
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spelling pubmed-87727982022-01-21 Ceftriaxone for the Treatment of Chronic Bacterial Prostatitis: A Case Series and Literature Review Kuiper, Sander G. Ploeger, Maarten Wilms, Erik B. van Dijk, Marleen M. Leegwater, Emiel Huis in’t Veld, Robert A. G. van Nieuwkoop, Cees Antibiotics (Basel) Brief Report Chronic bacterial prostatitis is increasingly difficult to treat due to rising antimicrobial resistance limiting oral treatment options. In this case series, 11 men with CBP (including patients with urological comorbidities) due to multi-resistant E. coli were treated with once-daily ceftriaxone intravenously for 6 weeks. Nine patients were clinically cured at 3 months follow up. No early withdrawal of medication due to side effects occurred. A literature review was conducted to describe the prostate pharmacokinetics of ceftriaxone and its use in prostatic infection. In conclusion, ceftriaxone can be considered an appropriate treatment of chronic bacterial prostatitis. MDPI 2022-01-11 /pmc/articles/PMC8772798/ /pubmed/35052960 http://dx.doi.org/10.3390/antibiotics11010083 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Kuiper, Sander G.
Ploeger, Maarten
Wilms, Erik B.
van Dijk, Marleen M.
Leegwater, Emiel
Huis in’t Veld, Robert A. G.
van Nieuwkoop, Cees
Ceftriaxone for the Treatment of Chronic Bacterial Prostatitis: A Case Series and Literature Review
title Ceftriaxone for the Treatment of Chronic Bacterial Prostatitis: A Case Series and Literature Review
title_full Ceftriaxone for the Treatment of Chronic Bacterial Prostatitis: A Case Series and Literature Review
title_fullStr Ceftriaxone for the Treatment of Chronic Bacterial Prostatitis: A Case Series and Literature Review
title_full_unstemmed Ceftriaxone for the Treatment of Chronic Bacterial Prostatitis: A Case Series and Literature Review
title_short Ceftriaxone for the Treatment of Chronic Bacterial Prostatitis: A Case Series and Literature Review
title_sort ceftriaxone for the treatment of chronic bacterial prostatitis: a case series and literature review
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772798/
https://www.ncbi.nlm.nih.gov/pubmed/35052960
http://dx.doi.org/10.3390/antibiotics11010083
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