Cargando…

ALDH1A3 Segregated Expression and Nucleus-Associated Proteasomal Degradation Are Common Traits of Glioblastoma Stem Cells

Aldehyde dehydrogenase 1 isoforms A1 and A3 have been implicated as functional biomarkers associated with distinct molecular subtypes of glioblastoma and glioblastoma stem cells. However, the exact roles of these isoforms in different types of glioma cells remain unclear. The purpose of this study w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fauß, Julian, Sprang, Bettina, Leukel, Petra, Sommer, Clemens, Nikolova, Teodora, Ringel, Florian, Kim, Ella L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772809/ https://www.ncbi.nlm.nih.gov/pubmed/35052687 http://dx.doi.org/10.3390/biomedicines10010007

Ejemplares similares

GARP as an Immune Regulatory Molecule in the Tumor Microenvironment of Glioblastoma Multiforme
por: Zimmer, Niklas, et al.
Publicado: (2019)

Senescence Is the Main Trait Induced by Temozolomide in Glioblastoma Cells
por: Beltzig, Lea, et al.
Publicado: (2022)

Intratumoral Heterogeneity and Longitudinal Changes in Gene Expression Predict Differential Drug Sensitivity in Newly Diagnosed and Recurrent Glioblastoma
por: Kim, Ella L., et al.
Publicado: (2020)

Localized Proteasomal Degradation: From the Nucleus to Cell Periphery
por: Guo, Xing
Publicado: (2022)

Identification of High-Risk Atypical Meningiomas According to Semantic and Radiomic Features
por: Kalasauskas, Darius, et al.
Publicado: (2020)

Proteasome inhibitors in glioblastoma
por: Huang, Wen-Juan, et al.
Publicado: (2017)

Proteasome inhibitors in glioblastoma
por: Huang, Wen-Juan, et al.
Publicado: (2017)

ALDH1-Mediated Autophagy Sensitizes Glioblastoma Cells to Ferroptosis
por: Wu, Yang, et al.
Publicado: (2022)

Proteasome in action: substrate degradation by the 26S proteasome
por: Sahu, Indrajit, et al.
Publicado: (2021)

Striatal increase of dopamine receptor 2 density in idiopathic and syndromic mouse models of autism spectrum disorder
por: Chhabra, Stuti, et al.
Publicado: (2023)

The proteasome and the degradation of oxidized proteins: Part II – protein oxidation and proteasomal degradation
por: Jung, Tobias, et al.
Publicado: (2013)

The Presence and Potential Role of ALDH1A2 in the Glioblastoma Microenvironment
por: Sanders, Stephanie, et al.
Publicado: (2021)

The proteasome and the degradation of oxidized proteins: Part I—structure of proteasomes()
por: Jung, Tobias, et al.
Publicado: (2013)

Segregation of Tactile Input Features in Neurons of the Cuneate Nucleus
por: Jörntell, Henrik, et al.
Publicado: (2014)

Neuroanatomical changes of ionotropic glutamatergic and GABAergic receptor densities in male mice modeling idiopathic and syndromic autism spectrum disorder
por: Nardi, Leonardo, et al.
Publicado: (2023)

Annexin A2 Stabilizes Oncogenic JAG1 Intracellular Domain by Inhibiting Proteasomal Degradation in Glioblastoma Cells
por: Ham, Seok Won, et al.
Publicado: (2023)

The Retrograde Connections and Anatomical Segregation of the Göttingen Minipig Nucleus Accumbens
por: Meidahl, Anders C., et al.
Publicado: (2016)

Regulation of Protein Degradation by Proteasomes in Cancer
por: Jang, Ho Hee
Publicado: (2018)

Golgi organization is regulated by proteasomal degradation
por: Eisenberg-Lerner, Avital, et al.
Publicado: (2020)

Functional Improvement after Photothrombotic Stroke in Rats Is Associated with Different Patterns of Dendritic Plasticity after G-CSF Treatment and G-CSF Treatment Combined with Concomitant or Sequential Constraint-Induced Movement Therapy
por: Frauenknecht, Katrin, et al.
Publicado: (2016)

The proteasome and the degradation of oxidized proteins: Part III—Redox regulation of the proteasomal system
por: Höhn, Tobias Jung Annika, et al.
Publicado: (2014)

ALDH1A3 induces mesenchymal differentiation and serves as a predictor for survival in glioblastoma
por: Li, Guanzhang, et al.
Publicado: (2018)

Enhanced Sensitivity to ALDH1A3-Dependent Ferroptosis in TMZ-Resistant Glioblastoma Cells
por: Wu, Yang, et al.
Publicado: (2023)

Proteins Directly Interacting with Mammalian 20S Proteasomal Subunits and Ubiquitin-Independent Proteasomal Degradation
por: Sánchez-Lanzas, Raúl, et al.
Publicado: (2014)

Proteasome storage granules protect proteasomes from autophagic degradation upon carbon starvation
por: Marshall, Richard S, et al.
Publicado: (2018)

Proteasome activator Blm10 levels and autophagic degradation directly impact the proteasome landscape
por: Burris, Alicia, et al.
Publicado: (2021)

Proteasomal degradation restricts the nuclear lifespan of AID
por: Aoufouchi, Said, et al.
Publicado: (2008)

Pathway choice between proteasomal and autophagic degradation
por: Lu, Kefeng, et al.
Publicado: (2017)

Proteasome-dependent degradation of intracellular carbamylated proteins
por: Desmons, Aurore, et al.
Publicado: (2019)

The Bacterial Proteasome at the Core of Diverse Degradation Pathways
por: Müller, Andreas U., et al.
Publicado: (2019)

Targeted Protein Degradation: Principles and Applications of the Proteasome
por: Kim, Yosup, et al.
Publicado: (2023)

ADP-Ribosylation Factor Like GTPase 4C (ARL4C) augments stem-like traits of glioblastoma cells by upregulating ALDH1A3
por: Chen, Qian, et al.
Publicado: (2021)

Ubiquitin–Proteasome-Dependent Regulation of Bidirectional Communication between Plastids and the Nucleus
por: Hirosawa, Yoshihiro, et al.
Publicado: (2017)

Proteasomal Inhibition Redirects the PrP-Like Shadoo Protein to the Nucleus
por: Kang, Sang-Gyun, et al.
Publicado: (2019)

The Hunt for Degrons of the 26S Proteasome
por: Ella, Hadar, et al.
Publicado: (2019)

Concurrent Activation of Both Survival-Promoting and Death-Inducing Signaling by Chloroquine in Glioblastoma Stem Cells: Implications for Potential Risks and Benefits of Using Chloroquine as Radiosensitizer
por: Müller, Andreas, et al.
Publicado: (2023)

The Proteasome Activators Blm10/PA200 Enhance the Proteasomal Degradation of N-Terminal Huntingtin
por: Aladdin, Azzam, et al.
Publicado: (2020)

Retraction: Proteasome storage granules protect proteasomes from autophagic degradation upon carbon starvation
por: Vierstra, Richard David
Publicado: (2022)

CHIP E3 ligase mediates proteasomal degradation of the proliferation regulatory protein ALDH1L1 during the transition of NIH3T3 fibroblasts from G(0)/G(1) to S-phase
por: Khan, Qasim A., et al.
Publicado: (2018)

Dopamine D1/D2 Receptor Activity in the Nucleus Accumbens Core But Not in the Nucleus Accumbens Shell and Orbitofrontal Cortex Modulates Risk-Based Decision Making
por: Mai, Bettina, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_so3ie2ttaqctchvfef2q8dfh3i