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Validation of Vancomycin Area under the Concentration—Time Curve Estimation by the Bayesian Approach Using One-Point Samples for Predicting Clinical Outcomes in Patients with Methicillin-Resistant Staphylococcus aureus Infections
Area under the concentration–time curve (AUC)-guided vancomycin treatment is associated with decreased nephrotoxicity. It is preferable to obtain two samples to estimate the AUC. This study examined the usefulness of AUC estimation via trough concentration (C(min))-only sampling of 260 adults infect...
Autores principales: | Ueda, Takashi, Takesue, Yoshio, Nakajima, Kazuhiko, Ichiki, Kaoru, Ishikawa, Kaori, Yamada, Kumiko, Tsuchida, Toshie, Otani, Naruhito, Takahashi, Yoshiko, Ishihara, Mika, Takubo, Shingo, Ikeuchi, Hiroki, Uchino, Motoi, Kimura, Toshimi, Matsumoto, Kazuaki, Oda, Kazutaka, Kimura, Takeshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772855/ https://www.ncbi.nlm.nih.gov/pubmed/35052972 http://dx.doi.org/10.3390/antibiotics11010096 |
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