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Validation of Vancomycin Area under the Concentration—Time Curve Estimation by the Bayesian Approach Using One-Point Samples for Predicting Clinical Outcomes in Patients with Methicillin-Resistant Staphylococcus aureus Infections

Area under the concentration–time curve (AUC)-guided vancomycin treatment is associated with decreased nephrotoxicity. It is preferable to obtain two samples to estimate the AUC. This study examined the usefulness of AUC estimation via trough concentration (C(min))-only sampling of 260 adults infect...

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Detalles Bibliográficos
Autores principales: Ueda, Takashi, Takesue, Yoshio, Nakajima, Kazuhiko, Ichiki, Kaoru, Ishikawa, Kaori, Yamada, Kumiko, Tsuchida, Toshie, Otani, Naruhito, Takahashi, Yoshiko, Ishihara, Mika, Takubo, Shingo, Ikeuchi, Hiroki, Uchino, Motoi, Kimura, Toshimi, Matsumoto, Kazuaki, Oda, Kazutaka, Kimura, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772855/
https://www.ncbi.nlm.nih.gov/pubmed/35052972
http://dx.doi.org/10.3390/antibiotics11010096

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