Macrophages Modulate Hepatic Injury Involving NLRP3 Inflammasome: The Example of Efavirenz

Drug-induced liver injury (DILI) constitutes a clinical challenge due to the incomplete characterization of the mechanisms involved and potential risk factors. Efavirenz, an anti-HIV drug, induces deleterious actions in hepatocytes that could underlie induction of the NLRP3 inflammasome, an importan...

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Detalles Bibliográficos
Autores principales: Alegre, Fernando, Martí-Rodrigo, Alberto, Polo, Miriam, Ortiz-Masiá, Dolores, Bañuls, Celia, Pinti, Marcello, Álvarez, Ángeles, Apostolova, Nadezda, Esplugues, Juan V., Blas-García, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772956/
https://www.ncbi.nlm.nih.gov/pubmed/35052789
http://dx.doi.org/10.3390/biomedicines10010109

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